5-amino-3-(2,3,5-tri-O-acetyl-beta-ribofuranosyl)thiazolo(4,5-d)pyrimidine-2,7-dione

Base Information

Chemical Name:5-amino-3-(2,3,5-tri-O-acetyl-beta-ribofuranosyl)thiazolo(4,5-d)pyrimidine-2,7-dione
CAS No.:124737-24-2
Molecular Formula:C16H18 N4 O9 S
Molecular Weight:442.406
Hs Code.:
Mol file:124737-24-2.mol

Synonyms:5-amino-3-(2,3,5-tri-O-acetyl-beta-ribofuranosyl)thiazolo(4,5-d)pyrimidine-2,7-dione

Suppliers and Price of 5-amino-3-(2,3,5-tri-O-acetyl-beta-ribofuranosyl)thiazolo(4,5-d)pyrimidine-2,7-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 5-amino-3-(2,3,5-tri-O-acetyl-beta-ribofuranosyl)thiazolo(4,5-d)pyrimidine-2,7-dione

Chemical Property:

Vapor Pressure:1.77E-13mmHg at 25°C
Boiling Point:580.7°Cat760mmHg
Flash Point:305°C
PSA：211.13000
Density:1.8g/cm³
LogP:-0.60520

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-amino-3-(2,3,5-tri-O-acetyl-beta-ribofuranosyl)thiazolo(4,5-d)pyrimidine-2,7-dione

There total 4 articles about 5-amino-3-(2,3,5-tri-O-acetyl-beta-ribofuranosyl)thiazolo(4,5-d)pyrimidine-2,7-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 122970-40-5
7-thia-8-oxoguanosine

: 108-24-7
acetic anhydride

: 124737-24-2
5-Amino-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)thiazolo[4,5-d]-pyrimidine-2,7(3H,6H)-dione

Guidance literature:: With dmap; triethylamine; In acetonitrile; at 0 - 20 ℃; for 2h;

Reference yield: 89.0%

: 122970-40-5
isatoribine

: 108-24-7
acetic anhydride

: 124737-24-2
5-Amino-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)thiazolo[4,5-d]-pyrimidine-2,7(3H,6H)-dione

Guidance literature:: With dmap; triethylamine; In acetonitrile; at 0 - 20 ℃; for 2h;

Reference yield:

: 30161-97-8
5-aminothiazolo<4,5-d>pyrimidine-2,7(3H,6H)-dione

: 39727-26-9
β-D-Ribofuranose-1,2,3,5-tetraacetate

: 124737-24-2
5-amino-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)thiazolo<4,5-d>pyrimidine-2,7-dione

Guidance literature:: With pyridine; ammonium sulfate; trimethylsilyl trifluoromethanesulfonate; 1,1,1,3,3,3-hexamethyl-disilazane; Yield given. Multistep reaction; 1.) reflux, 4 h, 2.) CH₃CN, RT, 16 h;
DOI:10.1021/jm00114a008