2-Methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)-1,4-naphthoquinone

Base Information

Chemical Name:2-Methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)-1,4-naphthoquinone
CAS No.:81818-54-4
Molecular Formula:C31H46O2
Molecular Weight:450.705
Hs Code.:
European Community (EC) Number:279-833-9,234-408-7
DSSTox Substance ID:DTXSID80859134
Wikidata:Q27166249,Q105161012
NCI Thesaurus Code:C943
ChEMBL ID:CHEMBL4549212
Mol file:81818-54-4.mol

Synonyms:Vitamin K

Suppliers and Price of 2-Methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)-1,4-naphthoquinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-Methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)-1,4-naphthoquinone

Chemical Property:

PSA：34.14000
LogP:9.15760
XLogP3:10.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:14
Exact Mass:450.349780706
Heavy Atom Count:33
Complexity:696

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)C2=CC=CC=C2C1=O)CC=C(C)CCCC(C)CCCC(C)CCCC(C)C
Recent EU Clinical Trials:The effect of administering VITamin K preprocedural on the vitamin K dependent coagulation factors and the INR in patients anticoagulated with ACEnocoumarol

Technology Process of 2-Methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)-1,4-naphthoquinone

There total 41 articles about 2-Methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)-1,4-naphthoquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 16869-68-4
trans-1,4-Dihydro-vitamin K₁⁽²⁰⁾

: 84-80-0,16033-41-3,27696-10-2,79082-95-4,79082-96-5,79082-97-6,79083-00-4,81818-54-4,105017-37-6,132487-93-5,132487-94-6,132487-95-7
vitamin K₁

Guidance literature:: With dihydrogen peroxide; (Bu₃SnO)2CrO₂ on charcoal; In ethanol; at 40 ℃; for 1.5h;
DOI:10.1246/cl.1986.2075

Reference yield: 56.0%

: 84-80-0,16033-41-3,27696-10-2,79082-95-4,79082-96-5,79082-97-6,79083-00-4,81818-54-4,105017-37-6,132487-93-5,132487-94-6,132487-95-7
vitamin K₁

Guidance literature:: With magnesium sulfate; silver(l) oxide; In diethyl ether;

Reference yield:

: 64648-85-7
2-Bromo-3-Methyl-1,1,4,4-tetramethoxy-1,4-dihydronaphthalene

: 943232-38-0
(7R,11R)-3,7,11,15-tetramethyl-2-hexadecenyl bromide

: 58-27-5,34524-96-4
menadione

: 84-80-0,16033-41-3,27696-10-2,79082-95-4,79082-96-5,79082-97-6,79083-00-4,81818-54-4,105017-37-6,132487-93-5,132487-94-6,132487-95-7
vitamin K₁

Guidance literature:: With hydrogenchloride; n-butyllithium; copper (I) iodide; dimethylsulfide; water; Yield given. Multistep reaction. Yields of byproduct given;
DOI:10.1021/jo01291a002