(R)-2-Cyclohexyl-propionic acid

Base Information

• Chemical Name: (R)-2-Cyclohexyl-propionic acid
• CAS No.: 3451-36-3
• Molecular Formula: C9H16O2
• Molecular Weight: 156.225
• Mol file: 3451-36-3.mol

Synonyms:(R)-2-cyclohexylpropanoic acid;(R)-2-Cyclohexylpropionsaeure;(R)-2-cyclohexyl-propionic acid;(R)-2-Cyclohexyl-propionsaeure;

Chemical Property of (R)-2-Cyclohexyl-propionic acid

Chemical Property:

• PSA: 37.30000
• LogP: 2.28740
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

(R)-2-Cyclohexyl-propionicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-2-Cyclohexyl-propionic acid

There total 13 articles about (R)-2-Cyclohexyl-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(R)-4-benzyl-3-((R)-2-cyclohexylpropanoyl)oxazolidin-2-one → (2R)-2-cyclohexylpropanoic acid (3451-36-3)

Guidance literature:

With dihydrogen peroxide; lithium hydroxide; In tetrahydrofuran; water; at 0 - 20 ℃; for 3h;

Reference yield: 70.0%

(1S,4R)-2-[(R)-2-Cyclohexyl-prop-(E)-ylidene]-1-isopropyl-4-methyl-cyclohexane (217321-16-9) → (2R)-2-cyclohexylpropanoic acid (3451-36-3)

Guidance literature:

(1S,4R)-2-[(R)-2-Cyclohexyl-prop-(E)-ylidene]-1-isopropyl-4-methyl-cyclohexane; With ozone; In dichloromethane; at -78 ℃;

With dihydrogen peroxide; In water; ethyl acetate; at 60 ℃; for 16h; Further stages.;

DOI:10.1021/jo000810t

Reference yield:

(+)-2-(1-cyclohexenyl)propanoic acid → (2R)-2-cyclohexylpropanoic acid (3451-36-3)

Guidance literature:

With hydrogen; palladium on barium sulfate; In methanol; under 760 Torr; Ambient temperature;

DOI:10.1246/bcsj.55.1677

upstream raw materials:

(R)-2-Phenylpropionic acid

[(1R,2E)-1-methyl-2-heptenyl]cyclohexane

(1S,4R)-2-[(R)-2-Cyclohexyl-prop-(E)-ylidene]-1-isopropyl-4-methyl-cyclohexane

S-Phenyl-S-((E)-1-trimethylsilyl-2-cyclohexylethenyl)-N-(toluene-p-sulfonyl)sulfoximine

Downstream raw materials:

(R)-2-cyclohexyl-propionic acid-chloride

(R)-2-Cyclohexyl-propionaldehyde

(R)-2-cyclohexyl-propionic acid amide

(R)-2-cyclohexyl-propionic acid nitrile