{(R)-2-[2-(1-Methyl-1H-tetrazol-5-ylsulfanyl)-acetylsulfanyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid acetoxymethyl ester

Base Information

• Chemical Name: {(R)-2-[2-(1-Methyl-1H-tetrazol-5-ylsulfanyl)-acetylsulfanyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid acetoxymethyl ester
• CAS No.: 74711-29-8
• Molecular Formula: C₃₀H₂₈N₅O₆PS₂
• Molecular Weight: 649.688

Synonyms:

Chemical Property of {(R)-2-[2-(1-Methyl-1H-tetrazol-5-ylsulfanyl)-acetylsulfanyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid acetoxymethyl ester

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Technology Process of {(R)-2-[2-(1-Methyl-1H-tetrazol-5-ylsulfanyl)-acetylsulfanyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid acetoxymethyl ester

There total 4 articles about {(R)-2-[2-(1-Methyl-1H-tetrazol-5-ylsulfanyl)-acetylsulfanyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid acetoxymethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4β-(1-bromomethyl)-vinylthio-1-[1-methoxycarbonyl-2-methyl-1-propenyl]-azetidin-2-one (74694-69-2) → {(R)-2-[2-(1-Methyl-1H-tetrazol-5-ylsulfanyl)-acetylsulfanyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ5-phosphanylidene)-acetic acid acetoxymethyl ester (74711-29-8)

Guidance literature:

DOI:10.1039/c39800000070

Reference yield:

(R)-2-[(R)-2-(3-Hydroxy-prop-1-ene-2-sulfinyl)-4-oxo-azetidin-1-yl]-3-methyl-but-3-enoic acid methyl ester (74694-68-1) → {(R)-2-[2-(1-Methyl-1H-tetrazol-5-ylsulfanyl)-acetylsulfanyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ5-phosphanylidene)-acetic acid acetoxymethyl ester (74711-29-8)

Guidance literature:

DOI:10.1039/c39800000070

Reference yield:

3-Methyl-2-{(R)-2-[1-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-vinylsulfanyl]-4-oxo-azetidin-1-yl}-but-2-enoic acid methyl ester (74694-70-5) → {(R)-2-[2-(1-Methyl-1H-tetrazol-5-ylsulfanyl)-acetylsulfanyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ5-phosphanylidene)-acetic acid acetoxymethyl ester (74711-29-8)

Guidance literature:

DOI:10.1039/c39800000070

upstream raw materials:

triphenylphosphine

(1-Methyl-1H-tetrazol-5-ylsulfanyl)-thioacetic acid S-((R)-4-oxo-azetidin-2-yl) ester

4β-(1-bromomethyl)-vinylthio-1-[1-methoxycarbonyl-2-methyl-1-propenyl]-azetidin-2-one

(R)-2-[(R)-2-(3-Hydroxy-prop-1-ene-2-sulfinyl)-4-oxo-azetidin-1-yl]-3-methyl-but-3-enoic acid methyl ester

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