Cyclopentanone, 2-[(R)-hydroxy(4-nitrophenyl)methyl]-, (2R)-

Base Information

Chemical Name:Cyclopentanone, 2-[(R)-hydroxy(4-nitrophenyl)methyl]-, (2R)-
CAS No.:349628-52-0
Molecular Formula:C12H13NO4
Molecular Weight:235.24
Hs Code.:
DSSTox Substance ID:DTXSID10454712
Nikkaji Number:J1.894.933D
Wikidata:Q82276397
Mol file:349628-52-0.mol

Synonyms:349628-52-0;Cyclopentanone, 2-[(R)-hydroxy(4-nitrophenyl)methyl]-, (2R)-;SCHEMBL13254450;DTXSID10454712;2beta-[(R)-alpha-Hydroxy-4-nitrobenzyl]cyclopentanone

Suppliers and Price of Cyclopentanone, 2-[(R)-hydroxy(4-nitrophenyl)methyl]-, (2R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of Cyclopentanone, 2-[(R)-hydroxy(4-nitrophenyl)methyl]-, (2R)-

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:235.08445790
Heavy Atom Count:17
Complexity:304

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C(=O)C1)C(C2=CC=C(C=C2)[N+](=O)[O-])O
Isomeric SMILES:C1C[C@@H](C(=O)C1)[C@H](C2=CC=C(C=C2)[N+](=O)[O-])O

Technology Process of Cyclopentanone, 2-[(R)-hydroxy(4-nitrophenyl)methyl]-, (2R)-

There total 19 articles about Cyclopentanone, 2-[(R)-hydroxy(4-nitrophenyl)methyl]-, (2R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 555-16-8
4-nitrobenzaldehdye

: 120-92-3
cyclopentanone

: 351533-04-5
(S)-2-[(R)-hydroxy(4-nitrophenyl)methyl]cyclopentanone

: 349628-52-0
(2R)-2-((R)-hydroxy(4-nitrophenyl)methyl)cyclopentan-1-one

Guidance literature:: With (S)-3-(5-amino-5-carboxypentyl)-5-decyl-1-methyl-3H-1,2,3-triazol-1-ium tetrafluoroborate; at 20 ℃; for 29h; optical yield given as %de; enantioselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2010.04.115

Reference yield: 87.0%

: 555-16-8
4-nitrobenzaldehdye

: 120-92-3
cyclopentanone

: 349628-52-0
(2R)-2-((R)-hydroxy(4-nitrophenyl)methyl)cyclopentan-1-one

Guidance literature:: 4-nitrobenzaldehdye; With (1R,2R)-N¹,N¹-dicyclopentylcyclohexane-1,2-diamine; tetrabutylammomium bromide; trifluoroacetic acid; In water; for 0.0833333h;

cyclopentanone; In water; at 0 ℃; for 72h; enantioselective reaction;
DOI:10.1016/j.tetlet.2013.09.053

Reference yield: 86.0%

: 555-16-8
4-nitrobenzaldehdye

: 120-92-3
cyclopentanone

: 205759-66-6
2-(hydroxy-(4-nitrophenyl)methyl)cyclopentan-1-one

: 349628-52-0
(2R)-2-((R)-hydroxy(4-nitrophenyl)methyl)cyclopentan-1-one

Guidance literature:: With L-proline; 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine tetraphenylborate; In neat (no solvent); at 0 - 3 ℃; for 120h; stereoselective reaction;
DOI:10.1021/jo3020352