3,4-Dichloro-1-benzothiophene-2-carbohydrazide

Base Information

• Chemical Name: 3,4-Dichloro-1-benzothiophene-2-carbohydrazide
• CAS No.: 350997-39-6
• Molecular Formula: C9H6Cl2N2OS
• Molecular Weight: 261.13
• DSSTox Substance ID: DTXSID901181016
• Pharos Ligand ID: M4WFQSL8NLHX
• ChEMBL ID: CHEMBL4441163
• Mol file: 350997-39-6.mol

Synonyms:3,4-dichloro-1-benzothiophene-2-carbohydrazide;350997-39-6;O8 OGG1 Inhibitor;3,4-dichlorobenzo[b]thiophene-2-carbohydrazide;OGG1 inhibitor O8;OGG1-IN-O8;OGG1-IN-08;3,4-Dichloro-benzo[b]thiophene-2-carboxylic acid hydrazide;CBMicro_031749;Cambridge id 6132595;O8 OGG1 Inhibitor- Bio-X;CHEMBL4441163;SCHEMBL18479792;BDBM163679;DTXSID901181016;EX-A3514;BBL037375;MFCD01993639;STK317634;AKOS003956278;BO167098;OGG1 Inhibitor O8, >=98% (HPLC);VS-14108;BIM-0031858.P001;HY-112902;CS-0067692;D83319;AB00102917-01;SR-01000228715;SR-01000228715-1;Benzo[b]thiophene-2-carboxylic acid, 3,4-dichloro-, hydrazide;3,4‐Dichloro‐1‐benzothiophene‐2‐carbohydrazide (08)

Chemical Property of 3,4-Dichloro-1-benzothiophene-2-carbohydrazide

Chemical Property:

• Storage Temp.: 2-8°C
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 259.9577894
• Heavy Atom Count: 15
• Complexity: 267

Purity/Quality:

97% ^*data from raw suppliers

O8OGG1Inhibitor ≥98%(HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC2=C(C(=C1)Cl)C(=C(S2)C(=O)NN)Cl
• Uses: O8 OGG1 Inhibitor is potent and selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor (IC50 = 0.2 μM in a gel based assay). Exhibits > 200-fold selectivity for OGG1 over other DNA glycosylases, NEIL1 and NTH1.