1,2-Bis[3-(trifluoromethyl)phenyl]hydrazine

Base Information

• Chemical Name: 1,2-Bis[3-(trifluoromethyl)phenyl]hydrazine
• CAS No.: 351-19-9
• Molecular Formula: C14H10F6N2
• Molecular Weight: 320.237
• DSSTox Substance ID: DTXSID10597557
• Nikkaji Number: J2.211.094B
• Wikidata: Q82493147
• Mol file: 351-19-9.mol

Synonyms:1,2-Bis[3-(trifluoromethyl)phenyl]hydrazine;351-19-9;1,2-bis(3-(trifluoromethyl)phenyl)hydrazine;SCHEMBL2925587;DTXSID10597557;WTUBIIQFZWOLMV-UHFFFAOYSA-N

Chemical Property of 1,2-Bis[3-(trifluoromethyl)phenyl]hydrazine

Chemical Property:

• XLogP3: 5.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 320.07481730
• Heavy Atom Count: 22
• Complexity: 320

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)NNC2=CC=CC(=C2)C(F)(F)F)C(F)(F)F
• Use Description: describe The uses Hydrazine, 1,2-bis[3-(trifluoromethyl)phenyl]-, a specific chemical compound, serves distinct roles in various fields. In the realm of organic synthesis and medicinal chemistry, it plays a pivotal role as a versatile building block for the creation of complex molecules and pharmaceutical compounds, contributing to drug discovery and the development of potential therapeutic agents. In the field of chemical research, this compound may be explored for its reactivity and potential applications in the synthesis of unique organic structures. Moreover, in the study of fluorinated compounds and their properties, it can serve as a model compound for investigating the behavior of trifluoromethyl-substituted molecules, advancing our understanding of organic chemistry and fluorine-containing compounds. Its applications in medicinal chemistry, chemical research, and the study of fluorinated compounds underscore its significance in driving innovation, scientific exploration, and potential medical breakthroughs within these distinct domains.of {ZEOLITE, HS-320, HYDROGEN Y} in different fields and the role played in each field in one paragraph in english

Technology Process of 1,2-Bis[3-(trifluoromethyl)phenyl]hydrazine

There total 2 articles about 1,2-Bis[3-(trifluoromethyl)phenyl]hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.8%

3-trifluoromethylnitrobenzene (98-46-4) → 1,2-bis(3-(trifluoromethyl)phenyl)hydrazine (351-19-9)

Guidance literature:

With sodium hydroxide; zinc; In methanol; water; toluene; at 50 - 70 ℃; for 13h; Inert atmosphere;

Reference yield: 92.0%

1,2-bis(3-(trifluoromethyl)phenyl)diazene (588-00-1) → 1,2-bis(3-(trifluoromethyl)phenyl)hydrazine (351-19-9)

Guidance literature:

With ammonium chloride; zinc; In acetone; at 15 - 20 ℃; for 0.0833333h; Irradiation;

DOI:10.1016/j.tetlet.2005.06.126

Reference yield: 95.1%

1,2-bis(3-(trifluoromethyl)phenyl)hydrazine (351-19-9) → 2,2'-bis(trifluoromethyl)benzidine (341-58-2)

Guidance literature:

With sulfuric acid; In water; toluene; for 5h; Product distribution / selectivity;

upstream raw materials:

3-trifluoromethylnitrobenzene

1,2-bis(3-(trifluoromethyl)phenyl)diazene

Downstream raw materials:

(3-trifluoromethyl)-N-isopropylbenzenamine

2,2'-bis(trifluoromethyl)benzidine

1,2-bis(3-(trifluoromethyl)phenyl)diazene