8-iso-prostaglandin A2

Base Information

• Chemical Name: 8-iso-prostaglandin A2
• CAS No.: 474391-66-7
• Molecular Formula: C20H30O4
• Molecular Weight: 334.4
• DSSTox Substance ID: DTXSID801348063
• Nikkaji Number: J1.063.722H
• Metabolomics Workbench ID: 2945
• ChEMBL ID: CHEMBL1083802
• Mol file: 474391-66-7.mol

Synonyms:15-A(2t)-IsoP;15-A(2t)-isoprostane;8-iso-prostaglandin A2;8-isoprostaglandin A2

Chemical Property of 8-iso-prostaglandin A2

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 12
• Exact Mass: 334.21440943
• Heavy Atom Count: 24
• Complexity: 476

Purity/Quality:

99% ^*data from raw suppliers

8-isoProstaglandinA2 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCC(C=CC1C=CC(=O)C1CC=CCCCC(=O)O)O
• Isomeric SMILES: CCCCC[C@@H](/C=C/[C@H]1C=CC(=O)[C@H]1C/C=C\CCCC(=O)O)O
• Description: Isoprostanes are prostaglandin (PG)-like compounds produced in vivo by free radical-catalyzed peroxidation of arachidonoyl-containing lipids. 8-iso PGA2 is one of several isoprostanes produced from peroxidation of arachidonic acid esterified in phospholipids. 8-iso PGA2 is the dehydration product of 8-iso PGE2, a potent renal vasoconstrictor. Evidence for the in vivo production of 8-iso PGA2 has been shown in rat liver under conditions of oxidative stress. There are no published studies of the pharmacological properties of 8-iso PGA2.