(6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate

Base Information

• Chemical Name: (6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate
• CAS No.: 1224606-06-7
• Molecular Formula: C43H79NO2
• Molecular Weight: 642.1
• UNII: Q0J6FQ6FKP
• Wikidata: Q108314971
• RXCUI: 2053488
• Mol file: 1224606-06-7.mol

Synonyms:D-Lin-MC3-DMA;1224606-06-7;DLin-MC3-DMA;(6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate;Q0J6FQ6FKP;[(6Z,9Z,28Z,31Z)-heptatriaconta-6,9,28,31-tetraen-19-yl] 4-(dimethylamino)butanoate;Butanoic acid, 4-(dimethylamino)-, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester;MC3;UNII-Q0J6FQ6FKP;DLIN-M-C3-DMA;SCHEMBL881351;DLin-M-C3-DMA Bulk Liquid;D-Lin-MC3-DMA (MC3);MC-3;NRLNQCOGCKAESA-KWXKLSQISA-N;RV-28;EX-A3031;ZYB60606;MFCD31657426;s6683;AKOS037648583;dilinoleylmethyl-4-dimethylaminobutyrate;AC-36309;BP-25497;BS-14715;HY-112251;CS-0044321;D80403;(6Z,9Z,28Z,31Z)-heptatriacont-6,9,28,31-tetraene-19-yl 4-(dimethylamino)butanoate;(6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl4-(dimethylamino)butanoate;[6Z,9Z,28Z,31Z)-heptatriaconta-6,9,28,31-tetraen-19-yl-4-(dimethylamino)butanoate

Chemical Property of (6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate

Chemical Property:

• PKA: 9.37±0.28(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Soluble in Ethanol, DMSO, DMF
• XLogP3: 16
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 36
• Exact Mass: 641.61108076
• Heavy Atom Count: 46
• Complexity: 687

Purity/Quality:

99% ^*data from raw suppliers

DLin-MC3-DMA >98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCC=CCC=CCCCCCCCCC(CCCCCCCCC=CCC=CCCCCC)OC(=O)CCCN(C)C
• Isomeric SMILES: CCCCC/C=C\C/C=C\CCCCCCCCC(OC(=O)CCCN(C)C)CCCCCCCC/C=C\C/C=C\CCCCC
• Description: D-Lin-MC3-DMA (MC3, DLin-MC3-DMA) is a potent and ionizable cationic lipid. D-Lin-MC3-DMA is used for delivery of siRNA in vivo. DLin-MC3-DMA, or (6Z,9Z,28Z,31Z)-heptatriacont-6,9,28,31-tetraene-19-yl 4-(dimethylamino)butanoate , is one of the most utilized cationic lipids that is used for making Lipid Nano-Particles (LNPs). These lipids, can form nanoparticles that can encapsulate and deliver siRNA, mRNA, DNA or small molecules into the cytoplasm and represent the most advanced delivery platforms for systemic administration of active molecules.