Chaetoviridin A

Base Information

Chemical Name:Chaetoviridin A
CAS No.:128252-98-2
Molecular Formula:C₂₃H₂₅ClO₆
Molecular Weight:432.901
Hs Code.:
DSSTox Substance ID:DTXSID80893270
Nikkaji Number:J350.902H
Wikidata:Q27136080
Metabolomics Workbench ID:124850
ChEMBL ID:CHEMBL1802150
Mol file:128252-98-2.mol

Synonyms:chaetoviridin A

Suppliers and Price of Chaetoviridin A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Chaetoviridin A
1mg
$ 346.00

TRC
ChaetoviridinA
2.5mg
$ 255.00

TRC
ChaetoviridinA
1mg
$ 125.00

AK Scientific
ChaetoviridinA
5mg
$ 638.00

Adipogen Life Sciences
ChaetoviridinA ≥96%(HPLC)
5 mg
$ 430.00

Total 7 raw suppliers

Chemical Property of Chaetoviridin A

Chemical Property:

Vapor Pressure:2.67E-17mmHg at 25°C
Melting Point:157-158℃
Boiling Point:607.6°C at 760 mmHg
PKA:14.36±0.20(Predicted)
Flash Point:321.3°C
PSA：89.90000
Density:1.31g/cm³
LogP:3.66040
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:432.1339662
Heavy Atom Count:30
Complexity:980

Purity/Quality:

98%Min ^*data from raw suppliers

Chaetoviridin A ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C)C=CC1=CC2=C(C(=O)C3(C(=C(C(=O)O3)C(=O)C(C)C(C)O)C2=CO1)C)Cl
Isomeric SMILES:CC[C@H](C)/C=C/C1=CC2=C(C(=O)[C@@]3(C(=C(C(=O)O3)C(=O)[C@@H](C)[C@@H](C)O)C2=CO1)C)Cl
Uses Chaetoviridin A is an azaphilone antibiotic that inhibits MAO and CETP. It can be used to promote inhibition of tumors.

Technology Process of Chaetoviridin A

There total 18 articles about Chaetoviridin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: C₂₉H₃₉ClO₆Si

: (7R,4’S,5’R,11S)-chaetoviridine A

: 128252-98-2
chaetoviridin A

Guidance literature:: With pyridine hydrogenfluoride; In tetrahydrofuran;
DOI:10.1021/acs.orglett.7b02053

Reference yield:

: 1403691-62-2
cazisochromene

: malonyl-CoA

: 485-80-3,15519-60-5,60018-85-1,60018-86-2,79845-28-6
S-adenosyl-L-methionine

: 128252-98-2
chaetoviridin A

Guidance literature:: With β-nicotinamide adenine dinucleotide 2'-phosphate reduced tetra(cyclohexylammonium) salt; acyltransferase CazE; recombinant CazF expressed from S_. cerevisiae BJ₅₄₆₄-NpgA²; In aq. phosphate buffer; at 20 ℃; for 1h; pH=7.4; Enzymatic reaction;
DOI:10.1021/ol401723h

Reference yield:

: methyl 3-chloro-4,6-bis(methoxymethoxy)-5-methyl-2-(2-oxo-2-(perfluorophenoxy)ethyl)benzoate

: (7R,4’S,5’R,11S)-chaetoviridine A

: 128252-98-2
chaetoviridin A

Guidance literature:: Multi-step reaction with 5 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

1.2: 1 h / -78 °C

2.1: diisobutylaluminium hydride / toluene / 0.33 h / -78 °C

3.1: trifluoroacetic acid; water; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dichloromethane / 3 h / 20 °C

4.1: toluene / 1.17 h / Molecular sieve; Reflux

4.2: 1 h / Molecular sieve; Reflux

5.1: pyridine hydrogenfluoride / tetrahydrofuran

With n-butyllithium; water; diisobutylaluminium hydride; pyridine hydrogenfluoride; trifluoroacetic acid; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; hexane; dichloromethane; toluene;
DOI:10.1021/acs.orglett.7b02053