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Technology Process of (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)azetidin-2-one

(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)azetidin-2-one

Base Information
  • Chemical Name:(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)azetidin-2-one
  • CAS No.:190595-66-5
  • Molecular Formula:C24H22FNO3
  • Molecular Weight:391.4
  • Hs Code.:
  • UNII:57H34XFV8F
  • Mol file:190595-66-5.mol
(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)azetidin-2-one

Synonyms:190595-66-5;(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)azetidin-2-one;EzetiMibe IMpurity 1;(3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-phenylpropyl]azetidin-2-one;(3'S,3R,4S)-Desfluoro Ezetimibe;57H34XFV8F;SCHEMBL8487782;AZKGJGUGALISLD-XPWALMASSA-N;3'S,3R,4S)-Desfluoro Ezetimibe;Desfluoro Ezetimibe, (3'S,3R,4S)-;(3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-phenylpropyl]-2-azetidinone;CS-0164702;F19353;A899491;(3 inverted exclamation mark S,3R,4S)-Desfluoro Ezetimibe;(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)azetidin-2-one? (Ezetimibe Impurity pound(c);(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-phenyl-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone;2-Azetidinone, 1-(4-fluorophenyl)-4-(4-hydroxyphenyl)-3-(3-hydroxy-3-phenylpropyl)-, [3R-[3alpha(S*),4beta]]-;2-Azetidinone, 1-(4-fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-phenylpropyl]-, (3R,4S)-

Suppliers and Price of (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)azetidin-2-one
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • (3’S,3R,4S)-DesfluoroEzetimibe
  • 100mg
  • $ 1455.00
  • American Custom Chemicals Corporation
  • EZETIMIBE DESFLURO IMPURITY A 95.00%
  • 5MG
  • $ 454.89
Total 14 raw suppliers
Chemical Property of (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)azetidin-2-one
Chemical Property:
  • PKA:9.72±0.30(Predicted) 
  • Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere 
  • Solubility.:Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly) 
  • XLogP3:3.9
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:6
  • Exact Mass:391.15837173
  • Heavy Atom Count:29
  • Complexity:536
Purity/Quality:

97% *data from raw suppliers

(3’S,3R,4S)-DesfluoroEzetimibe *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Canonical SMILES:C1=CC=C(C=C1)C(CCC2C(N(C2=O)C3=CC=C(C=C3)F)C4=CC=C(C=C4)O)O
  • Isomeric SMILES:C1=CC=C(C=C1)[C@H](CC[C@@H]2[C@H](N(C2=O)C3=CC=C(C=C3)F)C4=CC=C(C=C4)O)O
  • Uses (3’S,3R,4S)-Desfluoro Ezetimibe is an impurity of the cholesterol absorption inhibitor Ezetimibe (E975000).
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