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Technology Process of Cangrelor tetrasodium

Cangrelor tetrasodium

Base Information
  • Chemical Name:Cangrelor tetrasodium
  • CAS No.:163706-36-3
  • Molecular Formula:C17H21Cl2F3N5Na4O12P3S2
  • Molecular Weight:864.3
  • Hs Code.:
  • European Community (EC) Number:813-784-1
  • UNII:2144G00Y7W
  • DSSTox Substance ID:DTXSID50167652
  • Wikidata:Q27162818
  • NCI Thesaurus Code:C76396
  • Pharos Ligand ID:2PP7NP1N8QA6
  • ChEMBL ID:CHEMBL1097279
  • Mol file:163706-36-3.mol
Cangrelor tetrasodium

Synonyms:AR C69931MX;AR-C69931MX;cangrelor;cangrelor tetrasodium;Kengreal;N(6)-(2-methylthioethyl)-2-(3,3,3-trifluoropropylthio)-5'-adenylic acid monoanhydride with dichloromethylenebis(phosphonic acid)

Suppliers and Price of Cangrelor tetrasodium
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • AR-C69931TetrasodiumSalt
  • 1mg
  • $ 90.00
  • Tocris
  • AR-C69931tetrasodiumsalt ≥98%(HPLC)
  • 1
  • $ 259.00
  • DC Chemicals
  • Cangrelorsodium >98%
  • 100 mg
  • $ 700.00
  • DC Chemicals
  • Cangrelorsodium
  • 002
  • $ 1300.00
  • Crysdot
  • Cangrelortetrasodium 95+%
  • 50mg
  • $ 410.00
  • Crysdot
  • Cangrelortetrasodium 95+%
  • 100mg
  • $ 655.00
  • ChemScene
  • Cangrelor(tetrasodium) 99.93%
  • 50mg
  • $ 550.00
  • ChemScene
  • Cangrelor(tetrasodium) 99.93%
  • 10mg
  • $ 190.00
  • ChemScene
  • Cangrelor(tetrasodium) 99.93%
  • 5mg
  • $ 120.00
  • Cayman Chemical
  • Cangrelor (sodium salt) ≥98%
  • 1mg
  • $ 199.00
Total 44 raw suppliers
Chemical Property of Cangrelor tetrasodium
Chemical Property:
  • Hydrogen Bond Donor Count:3
  • Hydrogen Bond Acceptor Count:21
  • Rotatable Bond Count:14
  • Exact Mass:862.8760915
  • Heavy Atom Count:48
  • Complexity:1110
Purity/Quality:

99%, *data from raw suppliers

AR-C69931TetrasodiumSalt *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CSCCNC1=C2C(=NC(=N1)SCCC(F)(F)F)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)(C(P(=O)([O-])[O-])(Cl)Cl)[O-])O)O.[Na+].[Na+].[Na+].[Na+]
  • Isomeric SMILES:CSCCNC1=C2C(=NC(=N1)SCCC(F)(F)F)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)(C(P(=O)([O-])[O-])(Cl)Cl)[O-])O)O.[Na+].[Na+].[Na+].[Na+]
  • Recent ClinicalTrials:Cangrelor vs. Ticagrelor for Early Platelet Inhibition in STEMI
  • Recent EU Clinical Trials:Preclinical antiplatelet treatment with Cangrelor in patients presenting with ST-Elevation myocardial infarction: a randomized, double-blind, placebo-controlled pilot trial
  • Description Cangrelor tetrasodium is a direct purinergic platelet receptor (P2Y12) inhibitor that blocks ADP-induced platelet activation and aggregation. The drug, which was developed by The Medicine Company, binds reversibly to the P2Y12 receptor, preventing further signaling and platelet activation. Cangrelor, which was approved in June 2015 by the FDA, is indicated as an adjunct to percutaneous coronary intervention for reducing the risk of periprocedural myocardial infarction, repeat coronary revascularization, and stent thrombosis in patients who have not been treated with a P2Y12 platelet inhibitor and are not being given a glycoprotein IIb/IIIa inhibitor. The most common side effect observed with the drug was bleeding.
  • Uses Antiplatelet agent.
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