5-Methoxy-1-benzofuran-2-carboxamide

Base Information

Chemical Name:5-Methoxy-1-benzofuran-2-carboxamide
CAS No.:35351-22-5
Molecular Formula:C₁₀H₉NO₃
Molecular Weight:191.186
Hs Code.:
DSSTox Substance ID:DTXSID50377633
Wikidata:Q82166919
Mol file:35351-22-5.mol

Synonyms:5-methoxy-1-benzofuran-2-carboxamide;35351-22-5;11P-624;Oprea1_834467;SCHEMBL5806070;DTXSID50377633;AKOS015991929

Suppliers and Price of 5-Methoxy-1-benzofuran-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-METHOXY-1-BENZOFURAN-2-CARBOXAMIDE 95.00%
5MG
$ 667.02

Total 3 raw suppliers

Chemical Property of 5-Methoxy-1-benzofuran-2-carboxamide

Chemical Property:

Boiling Point:396.2±22.0 °C(Predicted)
PKA:15.55±0.30(Predicted)
PSA：66.45000
Density:1.282±0.06 g/cm3(Predicted)
LogP:2.42450
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:191.058243149
Heavy Atom Count:14
Complexity:231

Purity/Quality:

99% ^*data from raw suppliers

5-METHOXY-1-BENZOFURAN-2-CARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)OC(=C2)C(=O)N

Technology Process of 5-Methoxy-1-benzofuran-2-carboxamide

There total 5 articles about 5-Methoxy-1-benzofuran-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 68898-11-3
(5-methoxybenzofuran-2-yl)carbonyl chloride

: 35351-22-5
methoxy-5 carboxamido-2 benzofuranne

Guidance literature:: With ammonium hydroxide; In water; at 20 ℃; Cooling with ice;
DOI:10.1016/j.ejmech.2021.113540

Reference yield:

: 10242-08-7
5-methoxybenzofuran-2-carboxylic acid

: 35351-22-5
methoxy-5 carboxamido-2 benzofuranne

Guidance literature:: 5-methoxybenzofuran-2-carboxylic acid; With thionyl chloride; In benzene;

With ammonia; In tetrahydrofuran;
DOI:10.1039/b102837p

Reference yield:

: 672-13-9
2-hydroxy-5-methoxybenzaldehyde

: 35351-22-5
methoxy-5 carboxamido-2 benzofuranne

Guidance literature:: Multi-step reaction with 3 steps

1.1: K₂CO₃ / butan-2-one

2.1: aq. KOH / ethanol

3.1: thionyl chloride / benzene

3.2: ammonia / tetrahydrofuran

With potassium hydroxide; thionyl chloride; potassium carbonate; In ethanol; butanone; benzene;
DOI:10.1039/b102837p