3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-[4-[2-(4-methoxyphenyl)-2-oxoethyl]-1- piperazinyl]-4-oxo-

Base Information

• Chemical Name: 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-[4-[2-(4-methoxyphenyl)-2-oxoethyl]-1- piperazinyl]-4-oxo-
• CAS No.: 353793-91-6
• Molecular Formula: C25H25F2N3O5
• Molecular Weight: 485.487
• Mol file: 353793-91-6.mol

Synonyms:

Chemical Property of 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-[4-[2-(4-methoxyphenyl)-2-oxoethyl]-1- piperazinyl]-4-oxo-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-[4-[2-(4-methoxyphenyl)-2-oxoethyl]-1- piperazinyl]-4-oxo-

There total 2 articles about 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-[4-[2-(4-methoxyphenyl)-2-oxoethyl]-1- piperazinyl]-4-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

8-fluoronorfloxacin (99726-76-8) + 2-Bromo-4'-methoxyacetophenone (2632-13-5) → 1-ethyl-6,8-difluoro-7-{4-[2-(4-methoxyphenyl)-2-oxoethyl]-1-piperazinyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (353793-91-6)

Guidance literature:

With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1021/jm0100335

Reference yield:

8-fluoronorfloxacin (99726-76-8) → 1-ethyl-6,8-difluoro-7-{4-[2-(4-methoxyphenyl)-2-oxoethyl]-1-piperazinyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (353793-91-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / KHCO₃; KI / dimethylformamide / 24 h / 20 °C

2: NaHCO₃ / dimethylformamide

With sodium hydrogencarbonate; potassium hydrogencarbonate; potassium iodide; In N,N-dimethyl-formamide;

DOI:10.1002/hlca.200390201

Reference yield: 87.0%

1-ethyl-6,8-difluoro-7-{4-[2-(4-methoxyphenyl)-2-oxoethyl]-1-piperazinyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (353793-91-6) → 1-ethyl-6,8-difluoro-7-{4-[2-hydroxyimino-2-(4-methoxyphenyl)ethyl]-1-piperazinyl}-4-oxo-1,4-dihyroquinoline-3-carboxylic acid

Guidance literature:

With hydroxylamine; In methanol; Heating;

DOI:10.1021/jm0100335

upstream raw materials:

8-fluoronorfloxacin

2-Bromo-4'-methoxyacetophenone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 353793-91-6 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-[4-[2-(4-methoxyphenyl)-2-oxoethyl]-1- piperazinyl]-4-oxo-

Send

Send

Metric Ton KG G Pound L ML

Send

Send