Amidinoproline

Base Information

• Chemical Name: Amidinoproline
• CAS No.: 35404-57-0
• Molecular Formula: C6H11N3O2
• Molecular Weight: 157.172
• UNII: 4EIW83811H
• DSSTox Substance ID: DTXSID00188892
• Nikkaji Number: J1.746.104D
• Wikidata: Q27259490
• Mol file: 35404-57-0.mol

Synonyms:AMIDINOPROLINE;35404-57-0;N-Guanylproline;1-Guanylproline;L-N-Amidinoproline;N-Amidino-L-proline;Proline, 1-amidino-;(S)-N-Amidinoproline;Amidinoproline [INCI];L-Proline, 1-(aminoiminomethyl)-;(2S)-1-carbamimidoylpyrrolidine-2-carboxylic acid;4EIW83811H;(S)-1-Carbamimidoylpyrrolidine-2-carboxylic acid;UNII-4EIW83811H;Guanidino-L-proline;N-carbamimidoyl-l-proline;SCHEMBL212486;DTXSID00188892;ZXPRYJHVDMWTMA-BYPYZUCNSA-N;Q27259490

Chemical Property of Amidinoproline

Chemical Property:

• PSA: 90.41000
• LogP: 0.16680
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 157.085126602
• Heavy Atom Count: 11
• Complexity: 192

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC(N(C1)C(=N)N)C(=O)O
• Isomeric SMILES: C1C[C@H](N(C1)C(=N)N)C(=O)O

Technology Process of Amidinoproline

There total 1 articles about Amidinoproline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-isourea (2440-60-0) + L-proline (147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7) → L-proline-N-carboxamidine (35404-57-0)

Guidance literature:

With methanol;

Reference yield: 56.0%

benzamide (55-21-0,27208-38-4) + L-proline-N-carboxamidine (35404-57-0) → C12H16N4O

Guidance literature:

L-proline-N-carboxamidine; With ammonium peroxydisulfate; copper(ll) sulfate pentahydrate; silver nitrate; In water; at 20 ℃; for 0.5h;

benzamide; In water; at 60 ℃; for 16h; Time;

DOI:10.3390/molecules25040797

Reference yield: 32.0%

3-phenylpropionamide (102-93-2) + L-proline-N-carboxamidine (35404-57-0) → C14H20N4O

Guidance literature:

L-proline-N-carboxamidine; With ammonium peroxydisulfate; copper(ll) sulfate pentahydrate; silver nitrate; In water; at 20 ℃; for 0.5h;

3-phenylpropionamide; In water; at 60 ℃;

DOI:10.3390/molecules25040797

upstream raw materials:

2-methyl-isourea

L-proline

Downstream raw materials:

N-[N¹-(2,4,6-trimethylphenylsulfonyl)carbamimidoyl]-L-proline

N-mesitylenesulfonylamidino-L-prolyl-L-alanine tert-butyl ester

N-amidino-2-hydroxypyrrolidine

N-amidino-2-pyrrolidone