5-Amino-2-(trifluoromethyl)benzonitrile

Base Information

Chemical Name:5-Amino-2-(trifluoromethyl)benzonitrile
CAS No.:354814-19-0
Molecular Formula:C8H5F3N2
Molecular Weight:186.136
Hs Code.:
European Community (EC) Number:849-898-3
DSSTox Substance ID:DTXSID90477666
Mol file:354814-19-0.mol

Synonyms:5-Amino-2-(trifluoromethyl)benzonitrile;354814-19-0;Benzonitrile, 5-amino-2-(trifluoromethyl)-;MFCD20694851;SCHEMBL324114;DTXSID90477666;CL9603;AKOS017529650;AS-46419;SY160136;CS-0162563;EN300-177624;Z1262629299

Suppliers and Price of 5-Amino-2-(trifluoromethyl)benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 5-Amino-2-(trifluoromethyl)benzonitrile

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:186.04048265
Heavy Atom Count:13
Complexity:227

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1N)C#N)C(F)(F)F

Technology Process of 5-Amino-2-(trifluoromethyl)benzonitrile

There total 1 articles about 5-Amino-2-(trifluoromethyl)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 240800-45-7
3-cyano-4-trifluoromethyl-1-fluorobenzene

: 354814-19-0
5-amino-2-(trifluoromethyl)benzonitrile

Guidance literature:: With ammonium hydroxide; In 1,4-dioxane; at 120 ℃; under 7600.51 Torr;

Reference yield: 85.0%

: 354814-19-0
5-amino-2-(trifluoromethyl)benzonitrile

: 259811-65-9
2-(5-((5-(4-chlorophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid

: 1152541-48-4
N-(3-cyano-4-(trifluoromethyl)benzyl)-5-((5-(4-chlorophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidine-3-carboxamide

Guidance literature:: 2-(5-((5-(4-chlorophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid; With tert-butyl chloroformate; triethylamine; In tetrahydrofuran; at 0 - 5 ℃; for 0.25h;

5-amino-2-(trifluoromethyl)benzonitrile; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/j.bmc.2009.01.016