4-Pyrimidinecarboxylic acid, 2-[(5R)-4,4-bis(4-fluorophenyl)-4,5-dihydro-5-[(methoxymethoxy)methyl] -1H-imidazol-2-yl]-, ethyl ester

Base Information

• Chemical Name: 4-Pyrimidinecarboxylic acid, 2-[(5R)-4,4-bis(4-fluorophenyl)-4,5-dihydro-5-[(methoxymethoxy)methyl] -1H-imidazol-2-yl]-, ethyl ester
• CAS No.: 357926-52-4
• Molecular Formula: C25H24F2N4O4
• Molecular Weight: 482.487
• Mol file: 357926-52-4.mol

Synonyms:

Chemical Property of 4-Pyrimidinecarboxylic acid, 2-[(5R)-4,4-bis(4-fluorophenyl)-4,5-dihydro-5-[(methoxymethoxy)methyl] -1H-imidazol-2-yl]-, ethyl ester

Chemical Property:

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Technology Process of 4-Pyrimidinecarboxylic acid, 2-[(5R)-4,4-bis(4-fluorophenyl)-4,5-dihydro-5-[(methoxymethoxy)methyl] -1H-imidazol-2-yl]-, ethyl ester

There total 1 articles about 4-Pyrimidinecarboxylic acid, 2-[(5R)-4,4-bis(4-fluorophenyl)-4,5-dihydro-5-[(methoxymethoxy)methyl] -1H-imidazol-2-yl]-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-cyano-4-pyrimidinecarboxylate (357926-58-0) + (2R)-1,1-bis(4-fluorophenyl)-3-{[(methyloxy)methyl]oxy}-1,2-propanediamine (357926-34-2) → (5R)-2-(4-ethoxycarbonyl-2-pyrimidyl)-4,4-bis(4-fluorophenyl)-5-[(methoxymethoxy)methyl]-2-imidazoline (357926-52-4)

Guidance literature:

scandium tris(trifluoromethanesulfonate); In toluene;

upstream raw materials:

ethyl 2-cyano-4-pyrimidinecarboxylate

(2R)-1,1-bis(4-fluorophenyl)-3-{[(methyloxy)methyl]oxy}-1,2-propanediamine

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