Imidazo[1,2-b]isoquinoline-5,10-dione

Base Information

Chemical Name:Imidazo[1,2-b]isoquinoline-5,10-dione
CAS No.:36142-27-5
Molecular Formula:C11H6N2O2
Molecular Weight:198.17800
Hs Code.:2933990090
DSSTox Substance ID:DTXSID60482989
Nikkaji Number:J3.093.087H
Wikidata:Q82319902
Mol file:36142-27-5.mol

Synonyms:imidazo[1,2-b]isoquinoline-5,10-dione;36142-27-5;5H,10H-imidazo[1,2-b]isoquinoline-5,10-dione;SCHEMBL11814492;DTXSID60482989;HMS1609D18;AKOS001378460;CS-0244174;EN300-27296;F0914-1521;Z235340119

Suppliers and Price of Imidazo[1,2-b]isoquinoline-5,10-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5H,10H-imidazo[1,2-b]isoquinoline-5,10-dione
250mg
$ 310.00

American Custom Chemicals Corporation
IMIDAZO[1,2-B]ISOQUINOLINE-5,10-DIONE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
IMIDAZO[1,2-B]ISOQUINOLINE-5,10-DIONE 95.00%
1G
$ 852.55

AccelPharmtech
Imidazo[1,2-b]isoquinoline-5,10-dione 97.00%
25G
$ 4010.00

AccelPharmtech
Imidazo[1,2-b]isoquinoline-5,10-dione 97.00%
5G
$ 2180.00

AccelPharmtech
Imidazo[1,2-b]isoquinoline-5,10-dione 97.00%
1G
$ 1940.00

Total 6 raw suppliers

Chemical Property of Imidazo[1,2-b]isoquinoline-5,10-dione

Chemical Property:

Melting Point:232-234 °C(Solv: acetonitrile (75-05-8))
Boiling Point:522.3±33.0 °C(Predicted)
PKA:-0.90±0.20(Predicted)
PSA：51.96000
Density:1.47±0.1 g/cm3(Predicted)
LogP:1.11600
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:198.042927438
Heavy Atom Count:15
Complexity:316

Purity/Quality:

98% ^*data from raw suppliers

5H,10H-imidazo[1,2-b]isoquinoline-5,10-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)C3=NC=CN3C2=O

Technology Process of Imidazo[1,2-b]isoquinoline-5,10-dione

There total 3 articles about Imidazo[1,2-b]isoquinoline-5,10-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 288-32-4
1H-imidazole

: 88-95-9
Phthaloyl dichloride

: 36142-27-5
Imidazo<1,2-b>isoquinolinone-5,10-dione

Guidance literature:: With acetic anhydride; at 90 ℃; for 0.25h;
DOI:10.1016/j.tetlet.2012.05.047

Reference yield:

: 88-99-3,73607-73-5
benzene-1,2-dicarboxylic acid

: 36142-27-5
Imidazo<1,2-b>isoquinolinone-5,10-dione

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 18 h / Reflux

2: acetic anhydride / 0.25 h / 90 °C

With thionyl chloride; acetic anhydride;
DOI:10.1016/j.tetlet.2012.05.047