4-(Bromomethyl)-3-fluorobenzoic acid

Base Information

Chemical Name:4-(Bromomethyl)-3-fluorobenzoic acid
CAS No.:361456-46-4
Molecular Formula:C8H6BrFO2
Molecular Weight:233.037
Hs Code.:2916310090
DSSTox Substance ID:DTXSID30568688
Wikidata:Q82455013
Mol file:361456-46-4.mol

Synonyms:4-(BROMOMETHYL)-3-FLUOROBENZOIC ACID;361456-46-4;MFCD11179690;SCHEMBL973055;DTXSID30568688;FRWSNDGNNMQGNU-UHFFFAOYSA-N;4-bromomethyl-3-fluorobenzoic acid;4-Bromomethyl-3-fluoro-benzoic acid;AKOS009305924;PS-9983;4-(bromomethyl)-3-fluoranyl-benzoic acid;SY261642;4-(BROMOMETHYL)-3-FLUOROBENZOICACID;C90464;A823140;4-Carboxy-2-fluorobenzyl bromide, alpha-Bromo-3-fluoro-p-toluic acid

Suppliers and Price of 4-(Bromomethyl)-3-fluorobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-(Bromomethyl)-3-fluorobenzoic acid
5 g
$ 960.00

SynQuest Laboratories
4-(Bromomethyl)-3-fluorobenzoic acid
250 mg
$ 160.00

SynQuest Laboratories
4-(Bromomethyl)-3-fluorobenzoic acid
1 g
$ 376.00

Apolloscientific
4-(Bromomethyl)-3-fluorobenzoicacid
1g
$ 341.00

Apolloscientific
4-(Bromomethyl)-3-fluorobenzoicacid
250mg
$ 145.00

Apolloscientific
4-(Bromomethyl)-3-fluorobenzoicacid
5g
$ 870.00

AK Scientific
4-(Bromomethyl)-3-fluorobenzoicacid
5g
$ 1207.00

Total 5 raw suppliers

Chemical Property of 4-(Bromomethyl)-3-fluorobenzoic acid

Chemical Property:

PSA：37.30000
LogP:2.41880
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:231.95352
Heavy Atom Count:12
Complexity:174

Purity/Quality:

97% ^*data from raw suppliers

4-(Bromomethyl)-3-fluorobenzoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(=O)O)F)CBr

Technology Process of 4-(Bromomethyl)-3-fluorobenzoic acid

There total 6 articles about 4-(Bromomethyl)-3-fluorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.1%

: 361456-46-4
4-(bromomethyl)-3-fluorobenzoic acid

Guidance literature:

Reference yield: 30.0%

: 350-28-7
3-fluoro-4-methyl-benzoic acid

: 361456-46-4
4-(bromomethyl)-3-fluorobenzoic acid

Guidance literature:: With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In chloroform; Reflux; Inert atmosphere;

Reference yield:

: 51436-99-8
2-fluoro-4-bromotoluene

: 361456-46-4
4-(bromomethyl)-3-fluorobenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 71.3 percent / Mg / tetrahydrofuran

2: 10.3 g / Br₂; AIBN / CCl₄ / 80 °C

With 2,2'-azobis(isobutyronitrile); bromine; magnesium; In tetrahydrofuran; tetrachloromethane;
DOI:10.1016/S0022-1139(02)00148-3