tert-Butyl ((S)-2-(3,5-difluorophenyl)-1-((R)-oxiran-2-yl)ethyl)carbamate

Base Information

Chemical Name:tert-Butyl ((S)-2-(3,5-difluorophenyl)-1-((R)-oxiran-2-yl)ethyl)carbamate
CAS No.:362480-04-4
Molecular Formula:C15H19F2NO3
Molecular Weight:299.318
Hs Code.:
DSSTox Substance ID:DTXSID60465217
Wikidata:Q82291008
Mol file:362480-04-4.mol

Synonyms:362480-04-4;tert-Butyl ((S)-2-(3,5-difluorophenyl)-1-((R)-oxiran-2-yl)ethyl)carbamate;tert-butyl N-[(1S)-2-(3,5-difluorophenyl)-1-[(2R)-oxiran-2-yl]ethyl]carbamate;starbld0000412;SCHEMBL3501789;DTXSID60465217;NKGKCDXMOMAORK-STQMWFEESA-N;AKOS016010632;tert-butyl (1S)-2-(3,5-difluorophenyl)-1-[(2R)-2-oxiranyl]ethylcarbamate;tert-Butyl (1S)-2-(3,5-difluorophenyl)-1-[(2R)-oxiranyl]ethylcarbamate;(1S, 2R)-[2-(3,5-Difluorophenyl)-1-oxiranylethyl]-carbamic acid tert-butyl ester;(1S,2R)-[2-(3,5-Difluorophenyl)-1-oxiranylethyl]-carbamic acid tert-butyl ester;Tert-Butyl (1S)-2-(3,5-difluorophenyl)-1-[(2R)-oxiran-2-yl]ethylcarbamate

Suppliers and Price of tert-Butyl ((S)-2-(3,5-difluorophenyl)-1-((R)-oxiran-2-yl)ethyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of tert-Butyl ((S)-2-(3,5-difluorophenyl)-1-((R)-oxiran-2-yl)ethyl)carbamate

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:299.13329979
Heavy Atom Count:21
Complexity:362

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC(=CC(=C1)F)F)C2CO2
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC1=CC(=CC(=C1)F)F)[C@@H]2CO2

Technology Process of tert-Butyl ((S)-2-(3,5-difluorophenyl)-1-((R)-oxiran-2-yl)ethyl)carbamate

There total 9 articles about tert-Butyl ((S)-2-(3,5-difluorophenyl)-1-((R)-oxiran-2-yl)ethyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₂H₂₇F₂NO₆S

: 362480-04-4
tert-butyl {(S)-2-(3,5-difluorophenyl)-1-[(R)-oxiran-2-yl]ethyl}carbamate

Guidance literature:: With potassium carbonate; In methanol; at 0 - 23 ℃; Inert atmosphere;
DOI:10.1016/j.tetlet.2017.09.025

Reference yield:

: 664372-71-8
C₁₁H₁₀ClF₂NO₂

: 24424-99-5
di-tert-butyl dicarbonate

: 362480-04-4
tert-butyl {(S)-2-(3,5-difluorophenyl)-1-[(R)-oxiran-2-yl]ethyl}carbamate

Guidance literature:: C₁₁H₁₀ClF₂NO₂; di-tert-butyl dicarbonate; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 1h;

With lithium hydroxide; In methanol; water; at 20 ℃; for 1h;