5-broMobenzo[c][1,2,5]oxadiazole oxide

Base Information

• Chemical Name: 5-broMobenzo[c][1,2,5]oxadiazole oxide
• CAS No.: 36387-84-5
• Molecular Formula: C6H3BrN2O2
• Molecular Weight: 215.006
• Mol file: 36387-84-5.mol

Synonyms:2,1,3-benzoxadiazole,5-bromo-,1-oxide;

Chemical Property of 5-broMobenzo[c][1,2,5]oxadiazole oxide

Chemical Property:

• PSA: 51.49000
• LogP: 2.01880

Purity/Quality:

98% ^*data from raw suppliers

5-BROMOBENZO[C][1,2,5]OXADIAZOLE-1-OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-broMobenzo[c][1,2,5]oxadiazole oxide

There total 1 articles about 5-broMobenzo[c][1,2,5]oxadiazole oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-bromo-2-nitroaniline (5228-61-5) → 4-bromo-9-oxido-8-oxa-7,9-diazabicyclo[4.3.0]nona-1(9),2,4,6-tetraene (36387-84-5)

Guidance literature:

With sodium hypochlorite solution; sodium hydroxide; In methanol;

DOI:10.1007/s00044-011-9660-y

Reference yield: 92.0%

4-bromo-9-oxido-8-oxa-7,9-diazabicyclo[4.3.0]nona-1(9),2,4,6-tetraene (36387-84-5) → 4-Bromo-benzene-1,2-diamine (1575-37-7)

Guidance literature:

With Saccharomyces cerevisiae BY; In methanol; at 20 ℃; for 6.5h; pH=7.0; aq. buffer; Enzymatic reaction;

DOI:10.1080/00397910802372509

Reference yield: 71.0%

4-bromo-9-oxido-8-oxa-7,9-diazabicyclo[4.3.0]nona-1(9),2,4,6-tetraene (36387-84-5) → 5-bromo-benzo[1,2,5]oxadiazole (51376-06-8)

Guidance literature:

With triethyl phosphite; In ethanol; at 60 ℃; for 1h; Inert atmosphere;

upstream raw materials:

5-bromo-2-nitroaniline

Downstream raw materials:

4-bromo-[1,2]benzoquinone dioxime

7-Bromo-3-hydroxymethyl-1,4-dioxy-quinoxaline-2-carboxylic acid phenethyl-amide

7-Bromo-3-hydroxymethyl-1,4-dioxy-quinoxaline-2-carboxylic acid (2-cyclohex-1-enyl-ethyl)-amide

7-Bromo-3-hydroxymethyl-1,4-dioxy-quinoxaline-2-carboxylic acid [2-(3,4-dimethoxy-phenyl)-ethyl]-amide