CID 53348188

Base Information

• Chemical Name: CID 53348188
• CAS No.: 1256152-35-8
• Molecular Formula: C32H39Cl2N7O4
• Molecular Weight: 656.6
• ChEMBL ID: CHEMBL2216830
• Mol file: 1256152-35-8.mol

Synonyms:FIIN-1;1256152-35-8;FIIN1;CHEMBL2216830;N-(3-((3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-(4-(diethylamino)butylamino)-2-oxo-3,4- dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)methyl)phenyl)acrylamide;N-(3-{[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-{[4-(diethylamino)butyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)prop-2-enamide;SCHEMBL17010767;BDBM50403060;AKOS040755818;NCGC00378818-01;HY-15813;TS-08872;CS-0009282;F95249;N-[3-[[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-[4-(diethylamino)butylamino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]methyl]phenyl]prop-2-enamide

Chemical Property of CID 53348188

Chemical Property:

• XLogP3: 5.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 15
• Exact Mass: 655.2440581
• Heavy Atom Count: 45
• Complexity: 947

Purity/Quality:

98% ^*data from raw suppliers

FIIN 1 hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCN(CC)CCCCNC1=NC=C2CN(C(=O)N(C2=N1)CC3=CC(=CC=C3)NC(=O)C=C)C4=C(C(=CC(=C4Cl)OC)OC)Cl
• Uses: FIIN-1 is a fibroblast growth factor receptor (FGFR) Irreversible Inhibitor 1.The fibroblast growth factor receptor tyrosine kinases are promising therapeutic targets in a number of cancers and FIIN-1 is a useful probe of FGFR-dependent cellular phenomena and may assist in the development of therapeutically relevant irreversible inhibitors, particularly for wild-type and drug-resistant forms of FGFR kinases. FIIN-1 is a fibroblast growth factor receptor (FGFR) Irreversible Inhibitor 1 (1).The fibroblast growth factor receptor tyrosine kinases are promising therapeutic targets in a number of cancers and FIIN-1 is a useful probe of FGFR-dependent cellular phenomena and may assist in the development of therapeutically relevant irreversible inhibitors, particularly for wild-type and drug-resistant forms of FGFR kinases.