3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid

Base Information

• Chemical Name: 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid
• CAS No.: 1334286-77-9
• Molecular Formula: C7H14O5
• Molecular Weight: 178.18
• Mol file: 1334286-77-9.mol

Synonyms:Hydroxy-PEG2-acid;1334286-77-9;3-[2-(2-hydroxyethoxy)ethoxy]propanoic acid;HO-PEG2-CH2CH2COOH;3-(2-(2-Hydroxyethoxy)ethoxy)propanoic acid;OH-PEG2-COOH;Hydroxy-PEG2 Acid;SCHEMBL2555371;WLZ3789;AKOS027439201;SB84096;BP-20526;BS-26791;HY-124380;3-(2-(2-Hydroxyethoxy)ethoxy)propanoicacid;CS-0086325;E85115

Chemical Property of 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid

Chemical Property:

• PKA: 4.27±0.10(Predicted)
• Solubility.: Soluble in Water, DMSO, DMF
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 178.08412354
• Heavy Atom Count: 12
• Complexity: 114

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-[2-(2-Hydroxyethoxy)ethoxy]propanoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(COCCOCCO)C(=O)O
• Description: Hydroxy-PEG2-acid sodium salt is a PEG linker containing a hydroxyl group with a terminal carboxylic acid (as sodium salt form). The free acid form is not stable due to the reaction of OH with PEG-COOH group to form polymer. The sodium salt form is stable for storage and shipping. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

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