STO-609 acetate

Base Information

• Chemical Name: STO-609 acetate
• CAS No.: 1173022-21-3
• Molecular Formula: C21H14N2O5
• Molecular Weight: 374.3
• ChEMBL ID: CHEMBL265470
• Mol file: 1173022-21-3.mol

Synonyms:STO-609 acetate;1173022-21-3;STO-609 (acetate);7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate;CHEMBL265470;1173022-21-3 (acetate);MFCD06411456;7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, monoacetate;STO-609-acetic acid;STO609 acetate;STO-609 acetate salt;11-oxo-3,10-diazapentacyclo[10.7.1.02,10.04,9.016,20]icosa-1(20),2,4,6,8,12,14,16,18-nonaene-17-carboxylic acid;SCHEMBL12479577;HMS3229O18;HMS3268E07;BCP19299;CCA02986;EX-A2462;YWB02221;C19H10N2O3.C2H4O2;HB0593;HY-19805A;AKOS024456660;CCG-206885;7-Oxo-7H-benzo[de]benzo[4,5]imidazo[2,1-a]isoquinoline-3-carboxylic Acid Acetate (1:1);AC-36079;AS-73033;SY265682;CS-0016740;P16961;STO-609-acetic acid, >=95% (HPLC), solid;SR-01000597813;STO-609 - CAS 52029-86-4;SR-01000597813-1;7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, acetate salt;11-oxo-3,10-diazapentacyclo[10.7.1.0(2),(1)?.0?,?.0(1)?,(2)?]icosa-1(19),2,4,6,8,12,14,16(20),17-nonaene-17-carboxylic acid;acetic acid;7-oxo-7H-benzo[de]benzo[4,5]imidazo[2,1-a]isoquinoline-3-carboxylic acid compound with acetic acid (1:1);7-OXO-7H-BENZO[DE]BENZO[4,5]IMIDAZO[2,1-A]ISOQUINOLINE-3-CARBOXYLIC ACID, ACETATE SALT

Chemical Property of STO-609 acetate

Chemical Property:

• Storage Temp.: 2-8°C
• Solubility.: Soluble in DMSO (up to 10 mg/ml).
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 374.09027155
• Heavy Atom Count: 28
• Complexity: 596

Purity/Quality:

99.3% ^*data from raw suppliers

STO-609Acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)O.C1=CC=C2C(=C1)N=C3N2C(=O)C4=CC=CC5=C(C=CC3=C54)C(=O)O
• Description: STO-609 (1173022-21-3) is a selective inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki = 80 and 15 ng/ml for inhibition of CaM-KKα and CaM-KKβ respectively).1 Binds to the? ATP-binding site.2 Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK. Important tool for probing distinct CaMK pathways in LTP.3 Reduces starvation-induced autophagosomal membrane formation.4 Reverses age-associated decline in bone mass.5 Stimulates osteoblast formation, inhibits osteoclast differentiation.6
• Uses: STO-609 is a cell-permeable inhibitor of calcium/calmodulin-dependent kinase kinases (CaMKK) isoforms CaMKKα and CaMKKβ. It is used to evaluate the action of CaMKK isoforms both in vitro and in cells.