Chemical Property of N-(R)-[2-(Hydroxyaminocarbonyl)methyl]-4-methylpentanoyl-L-t-butyl-alanyl-L-alanine, 2-aminoethyl Amide
Chemical Property:
- Sensitive.:Light Sensitive & Hygroscopic
- XLogP3:-0.1
- Hydrogen Bond Donor Count:6
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:12
- Exact Mass:415.27946930
- Heavy Atom Count:29
- Complexity:574
- Purity/Quality:
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99%, *data from raw suppliers
TAPI-2 *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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Useful:
- Canonical SMILES:CC(C)CC(CC(=O)NO)C(=O)NC(C(=O)NC(C)C(=O)NCCN)C(C)(C)C
- Isomeric SMILES:C[C@@H](C(=O)NCCN)NC(=O)[C@H](C(C)(C)C)NC(=O)C(CC(C)C)CC(=O)NO
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Uses
N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide is a TACE inhibitor. Inhibits the secretase in pig kidney microvillar membranes. A hydroxamate-based inhibitor of MMPs and TACE