Chemical Property of CID 100943561
Chemical Property:
- XLogP3:8.5
- Hydrogen Bond Donor Count:5
- Hydrogen Bond Acceptor Count:10
- Rotatable Bond Count:7
- Exact Mass:854.3312014
- Heavy Atom Count:59
- Complexity:1880
- Purity/Quality:
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>95% by HPLC *data from raw suppliers
DecatromicinB *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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Useful:
- Canonical SMILES:CCC1CC23C(=O)C(=C(C4(C5CCC(C(C5C=CC4CC=CCC(=CC2(C=C1C(=O)O)C)C)OC6CC(C(C(O6)C)NC(=O)C7=C(C=C(N7)Cl)Cl)O)C)CC)O)C(=O)O3
- Isomeric SMILES:CC[C@H]1C[C@@]23C(=O)C(=C([C@]4([C@@H]5CC[C@@H]([C@@H]([C@H]5C=C[C@H]4C/C=C/C/C(=C\[C@@]2(C=C1C(=O)O)C)/C)O[C@H]6C[C@H]([C@@H]([C@H](O6)C)NC(=O)C7=C(C=C(N7)Cl)Cl)O)C)CC)O)C(=O)O3
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Uses
Decatromicin B is a tetronic acid isolated from a strain of Actinomadura in 1999. Decatromicin B is a potent antibiotic with activity against antibiotic sensitive and resistant strains such as MRSA. Lack of availability has hampered further investigation into the mode of action or antibacterial spectrum of the decatromicins. Decatromicin B is a potent antibiotic with activity against sensitive and resistant straints.
