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Technology Process of N-Tert-Butyl-1-(1-{5-[5-(Trifluoromethyl)-1,3,4-Oxadiazol-2-Yl]pyridin-2-Yl}piperidin-4-Yl)-1h-Imidazole-5-Carboxamide

N-Tert-Butyl-1-(1-{5-[5-(Trifluoromethyl)-1,3,4-Oxadiazol-2-Yl]pyridin-2-Yl}piperidin-4-Yl)-1h-Imidazole-5-Carboxamide

Base Information
  • Chemical Name:N-Tert-Butyl-1-(1-{5-[5-(Trifluoromethyl)-1,3,4-Oxadiazol-2-Yl]pyridin-2-Yl}piperidin-4-Yl)-1h-Imidazole-5-Carboxamide
  • CAS No.:2012607-27-9
  • Molecular Formula:C21H24F3N7O2
  • Molecular Weight:463.5
  • Hs Code.:
  • Nikkaji Number:J3.591.084K
  • Wikidata:Q27455714
  • Mol file:2012607-27-9.mol
N-Tert-Butyl-1-(1-{5-[5-(Trifluoromethyl)-1,3,4-Oxadiazol-2-Yl]pyridin-2-Yl}piperidin-4-Yl)-1h-Imidazole-5-Carboxamide

Synonyms:N-(tert-butyl)-1-(1-(5-(5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl)pyridin-2-yl)piperidin-4-yl)-1H-imidazole-5-carboxamide;WNK463

Suppliers and Price of N-Tert-Butyl-1-(1-{5-[5-(Trifluoromethyl)-1,3,4-Oxadiazol-2-Yl]pyridin-2-Yl}piperidin-4-Yl)-1h-Imidazole-5-Carboxamide
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • WNK463
  • 5mg
  • $ 360.00
  • Sigma-Aldrich
  • WNK463 ≥98% (HPLC)
  • 25MG
  • $ 379.00
  • Sigma-Aldrich
  • WNK463 ≥98% (HPLC)
  • 5MG
  • $ 99.00
  • DC Chemicals
  • WNK463 >98%
  • 250 mg
  • $ 1300.00
  • CSNpharm
  • WNK463
  • 10mg
  • $ 242.00
  • CSNpharm
  • WNK463
  • 5mg
  • $ 163.00
  • Crysdot
  • WNK463 98%
  • 100mg
  • $ 495.00
  • Crysdot
  • WNK463 98%
  • 1g
  • $ 1850.00
  • Crysdot
  • WNK463 98%
  • 250mg
  • $ 740.00
  • ChemScene
  • WNK463 99.55%
  • 100mg
  • $ 1200.00
Total 13 raw suppliers
Chemical Property of N-Tert-Butyl-1-(1-{5-[5-(Trifluoromethyl)-1,3,4-Oxadiazol-2-Yl]pyridin-2-Yl}piperidin-4-Yl)-1h-Imidazole-5-Carboxamide
Chemical Property:
  • PKA:15.18±0.46(Predicted) 
  • Storage Temp.:2-8°C 
  • XLogP3:2.6
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:10
  • Rotatable Bond Count:5
  • Exact Mass:463.19435752
  • Heavy Atom Count:33
  • Complexity:682
Purity/Quality:

99%, *data from raw suppliers

WNK463 *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Canonical SMILES:CC(C)(C)NC(=O)C1=CN=CN1C2CCN(CC2)C3=NC=C(C=C3)C4=NN=C(O4)C(F)(F)F
  • Uses WNK 463, is a pan-WNK kinase inhibitor, acting on WNK1, WNK2, WNK3, and WNK4 kinases. It has shown to affect blood pressure, heart rate, body fluid and electrolyte homeostasis in rodent models of hypertension.
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