5(S)-Hete

Base Information

• Chemical Name: 5(S)-Hete
• CAS No.: 330796-62-8
• Molecular Formula: C20H32O3
• Molecular Weight: 328.5
• European Community (EC) Number: 633-222-7
• UNII: 467RNW8T91
• ChEMBL ID: CHEMBL164813
• DSSTox Substance ID: DTXSID701017281
• Metabolomics Workbench ID: 2629
• NCI Thesaurus Code: C558
• Nikkaji Number: J390.336B
• Wikidata: Q2823230
• Wikipedia: 5-Hydroxyeicosatetraenoic_acid
• Mol file: 330796-62-8.mol

Synonyms:5-HETE;5-hydroxy-6,8,11,14-eicosatetraenoic acid;5-hydroxy-6,8,11,14-eicosatetraenoic acid, (E,E,Z,Z)-isomer;5-hydroxy-6,8,11,14-eicosatetraenoic acid, (E,Z,Z,Z)-(+-)-isomer;5-hydroxy-6,8,11,14-eicosatetraenoic acid, (E,Z,Z,Z)-isomer;5-hydroxy-6,8,11,14-eicosatetraenoic acid, (S)-(E,Z,Z,Z)-isomer;5-hydroxy-6,8,11,14-eicosatetraenoic acid, R-(E,Z,Z,Z)-isomer;5-hydroxyeicosatetraenoic acid

Chemical Property of 5(S)-Hete

Chemical Property:

• XLogP3: 5.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 14
• Exact Mass: 320.23514488
• Heavy Atom Count: 23
• Complexity: 392

Purity/Quality:

99% ^*data from raw suppliers

5(S)-HETE-d8 ≥99% deuterated forms (d1-d8) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCC=CCC=CCC=CC=CC(CCCC(=O)O)O
• Isomeric SMILES: CCCCC/C=C\C/C=C\C/C=C\C=C\[C@H](CCCC(=O)O)O
• Uses: 5(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 5(S)-HETE by GC- or LC-mass spectrometry (MS). 5(S)-HETE is produced by the action of 5-lipoxygenase on arachidonic acid to give 5(S)-HpETE, followed by reduction of the hydroperoxide. 5(S)-HETE has proliferative and chemotactic effects on granulocytes. When further metabolized to the 5-oxoETE, it is a more potent eosinophil chemoattractant than leukotriene B4.