3-[(4-Nitrophenyl)carbamoyl]prop-2-enoic acid

Base Information

• Chemical Name: 3-[(4-Nitrophenyl)carbamoyl]prop-2-enoic acid
• CAS No.: 36847-91-3
• Molecular Formula: C₁₀H₈N₂O₅
• Molecular Weight: 236.184
• DSSTox Substance ID: DTXSID901249296
• Mol file: 36847-91-3.mol

Synonyms:3-[(4-nitrophenyl)carbamoyl]prop-2-enoic acid;36342-10-6;DTXSID901249296

Chemical Property of 3-[(4-Nitrophenyl)carbamoyl]prop-2-enoic acid

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 236.04332136
• Heavy Atom Count: 17
• Complexity: 339

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC=C1NC(=O)C=CC(=O)O)[N+](=O)[O-]

Technology Process of 3-[(4-Nitrophenyl)carbamoyl]prop-2-enoic acid

There total 4 articles about 3-[(4-Nitrophenyl)carbamoyl]prop-2-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

maleic anhydride (108-31-6) + 4-nitro-aniline (100-01-6,104810-17-5) → 4-(4-nitrophenylamino)-4-oxobut-2-enoic acid (36342-10-6,36847-91-3,37904-21-5)

Guidance literature:

at 18 - 52 ℃; zeitlicher Verlauf;

Reference yield:

fumaryl dichloride (627-63-4) + 4-nitro-aniline (100-01-6,104810-17-5) → 4-(4-nitrophenylamino)-4-oxobut-2-enoic acid (36342-10-6,36847-91-3,37904-21-5)

Guidance literature:

With chloroform;

DOI:10.1021/ja01640a002

Reference yield:

maleic anhydride (108-31-6) + 4-nitro-N-(phenylmethylene)benzenamine (785-81-9,1613-94-1,40339-44-4) → 4-(4-nitrophenylamino)-4-oxobut-2-enoic acid (36342-10-6,36847-91-3,37904-21-5)

Guidance literature:

With toluene;

DOI:10.1016/S1067-2516(01)80084-3

upstream raw materials:

maleic anhydride

4-nitro-aniline

4-nitro-N-(phenylmethylene)benzenamine

fumaryl dichloride

Downstream raw materials:

N-(4-nitrophenyl)maleimide

3-chloro-1-(4-nitrophenyl)pyrrolidine-2,5-dione

6β-[3-(4-nitro-phenylcarbamoyl)-acryloylamino]-penicillanic acid

tert-butyl 3-(4-nitrophenyl)-2,4-dioxo-3-azabicyclo[3.1.0]hexane-6-carboxylate