Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

Technology Process of 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione

6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione

Base Information
  • Chemical Name:6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione
  • CAS No.:863588-32-3
  • Molecular Formula:C20H25ClN4O2
  • Molecular Weight:388.9
  • Hs Code.:
  • ChEMBL ID:CHEMBL1325149
  • Wikidata:Q27164671
  • Mol file:863588-32-3.mol
6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione

Synonyms:863588-32-3;ML-180;ML180;6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione;MLS000094380;6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione;6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione;MLS003153119;SMR000029966;6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione;6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione;6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine-2,4(1H,3H)-dione;SR-01000621848;CHEMBL1325149;BDBM38962;CHEBI:92931;cid_3238389;HMS2179J14;EX-A4974;SR1848SR1848;AKOS024596931;CCG-310275;ML-180 (SR1848);AC-36583;AS-16640;HY-115613;SR1848, >=98% (HPLC);CS-0104030;E75018;SR-01000621848-2;SR-01000621848-3;6-[4-(3-chlorophenyl)piperazino]-3-cyclohexyl-uracil;Q27164671;F0693-1098

Suppliers and Price of 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • DC Chemicals
  • ML-180(SR1848)
  • 002
  • $ 1000.00
  • DC Chemicals
  • ML-180(SR1848)
  • 003
  • $ 2000.00
  • DC Chemicals
  • ML-180(SR1848)
  • 001
  • $ 600.00
  • CSNpharm
  • ML-180
  • 100mg
  • $ 630.00
  • CSNpharm
  • ML-180
  • 10mg
  • $ 120.00
  • CSNpharm
  • ML-180
  • 5mg
  • $ 75.00
  • CSNpharm
  • ML-180
  • 1mg
  • $ 47.00
  • Cayman Chemical
  • ML-180 ≥98%
  • 25mg
  • $ 307.00
  • Cayman Chemical
  • ML-180 ≥98%
  • 1mg
  • $ 32.00
  • Cayman Chemical
  • ML-180 ≥98%
  • 10mg
  • $ 142.00
Total 24 raw suppliers
Chemical Property of 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione
Chemical Property:
  • PKA:9.37±0.40(Predicted) 
  • Storage Temp.:2-8°C 
  • XLogP3:3.6
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:3
  • Exact Mass:388.1666037
  • Heavy Atom Count:27
  • Complexity:597
Purity/Quality:

99%, *data from raw suppliers

ML-180(SR1848) *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Canonical SMILES:C1CCC(CC1)N2C(=O)C=C(NC2=O)N3CCN(CC3)C4=CC(=CC=C4)Cl
  • Description ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 μM) with maximum efficacy of 64% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC50 = 2.05 μM).
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 863588-32-3

Total 8 Pictures about this product