Ethyl 4-(1,1,2,2-tetrafluoroethoxy)benzoate

Base Information

Chemical Name:Ethyl 4-(1,1,2,2-tetrafluoroethoxy)benzoate
CAS No.:37178-69-1
Molecular Formula:C11H10F4O3
Molecular Weight:266.18900
Hs Code.:2918990090
DSSTox Substance ID:DTXSID80476087
Nikkaji Number:J1.804.726H
Wikidata:Q72477281
Mol file:37178-69-1.mol

Synonyms:ETHYL 4-(1,1,2,2-TETRAFLUOROETHOXY)BENZOATE;37178-69-1;Ethyl-4-(1,1,2,2-tetrafluoroethoxy)benzoate;DTXSID80476087;DKRAOHBKQLAFRQ-UHFFFAOYSA-N;Benzoic acid, 4-(1,1,2,2-tetrafluoroethoxy)-, ethyl ester

Suppliers and Price of Ethyl 4-(1,1,2,2-tetrafluoroethoxy)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Ethyl 4-(1,1,2,2-tetrafluoroethoxy)benzoate 99%
25 g
$ 95.00

SynQuest Laboratories
Ethyl 4-(1,1,2,2-tetrafluoroethoxy)benzoate 99%
5 g
$ 35.00

SynQuest Laboratories
Ethyl 4-(1,1,2,2-tetrafluoroethoxy)benzoate 99%
1 g
$ 20.00

American Custom Chemicals Corporation
ETHYL-4-(1,1,2,2-TETRAFLUOROETHOXY)BENZOATE 95.00%
5MG
$ 503.53

Total 18 raw suppliers

Chemical Property of Ethyl 4-(1,1,2,2-tetrafluoroethoxy)benzoate

Chemical Property:

Refractive Index:1.44605
Boiling Point:244oC
Flash Point:116oC
PSA：35.53000
Density:1.2849
LogP:3.10000
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:266.05660683
Heavy Atom Count:18
Complexity:276

Purity/Quality:

99% ^*data from raw suppliers

Ethyl 4-(1,1,2,2-tetrafluoroethoxy)benzoate 99% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC=C(C=C1)OC(C(F)F)(F)F

Technology Process of Ethyl 4-(1,1,2,2-tetrafluoroethoxy)benzoate

There total 3 articles about Ethyl 4-(1,1,2,2-tetrafluoroethoxy)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 120-47-8
Ethyl 4-hydroxybenzoate

: 354-41-6
iodo-1,1,2,2,-tetrafluoroethane

: 37178-69-1
p-Ethoxycarbonyl-1,1,2,2-tetrafluorethylether

Guidance literature:: With potassium fluoride; In dimethyl sulfoxide; at 120 - 130 ℃; for 6h;
DOI:10.1016/S0040-4039(02)01719-7

Reference yield:

: ethyl 4-(2-bromo-1,1,2,2-tetrafluoroethoxy)benzoate

: 37178-69-1
p-Ethoxycarbonyl-1,1,2,2-tetrafluorethylether

Guidance literature:: ethyl 4-(2-bromo-1,1,2,2-tetrafluoroethoxy)benzoate; With TurboGrignard; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere; Schlenk technique;

With acetic acid; In tetrahydrofuran; at -78 ℃; for 0.0833333h; Reagent/catalyst; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.orglett.6b02890