Technology Process of Carbamic acid,
[2-[4-(6-bromohexyl)-2,5-dimethoxyphenyl]-1-methylethyl]-,
1,1-dimethylethyl ester
There total 10 articles about Carbamic acid,
[2-[4-(6-bromohexyl)-2,5-dimethoxyphenyl]-1-methylethyl]-,
1,1-dimethylethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-Bromosuccinimide; triphenylphosphine;
In
dichloromethane;
at 0 - 22 ℃;
DOI:10.3390/71100777
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 94 percent / conc. H2SO4 / 18 h / Heating
2.1: 33 percent / zinc amalgam; conc. HCl / methanol / 3 h / Heating
3.1: phosphorus oxychloride / 2 h / Heating
3.2: 35 percent / H2O / 18 h / 20 °C
4.1: 35 percent / ammonium acetate / acetic acid / 4 h / Heating
5.1: 66 percent / lithium aluminum hydride / diethyl ether / 48 h / Heating
6.1: HCl / methanol
6.2: 47 percent / potassium carbonate / H2O / 20 °C
7.1: 30 percent / triphenylphosphine; N-bromosuccinimide / CH2Cl2 / 0 - 22 °C
With
ammonium acetate; hydrogenchloride; amalgamated zinc; N-Bromosuccinimide; lithium aluminium tetrahydride; sulfuric acid; triphenylphosphine; trichlorophosphate;
In
methanol; diethyl ether; dichloromethane; acetic acid;
3.1: Vilsmeier-Haack formylation;
DOI:10.3390/71100777
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: aluminum chloride / nitrobenzene / 23 h / 0 - 20 °C
2.1: 11.4 g / 3 M NaOH
3.1: 94 percent / conc. H2SO4 / 18 h / Heating
4.1: 33 percent / zinc amalgam; conc. HCl / methanol / 3 h / Heating
5.1: phosphorus oxychloride / 2 h / Heating
5.2: 35 percent / H2O / 18 h / 20 °C
6.1: 35 percent / ammonium acetate / acetic acid / 4 h / Heating
7.1: 66 percent / lithium aluminum hydride / diethyl ether / 48 h / Heating
8.1: HCl / methanol
8.2: 47 percent / potassium carbonate / H2O / 20 °C
9.1: 30 percent / triphenylphosphine; N-bromosuccinimide / CH2Cl2 / 0 - 22 °C
With
ammonium acetate; hydrogenchloride; sodium hydroxide; amalgamated zinc; N-Bromosuccinimide; lithium aluminium tetrahydride; aluminium trichloride; sulfuric acid; triphenylphosphine; trichlorophosphate;
In
methanol; diethyl ether; dichloromethane; acetic acid; nitrobenzene;
1.1: Friedel-Crafts acylation / 5.1: Vilsmeier-Haack formylation;
DOI:10.3390/71100777
![6-(2,5-dimethoxy-4-(2-[N-(tert-butoxycarbonyl)]aminopropyl)phenyl)hexanol](/Databaselist/images/loading.webp)
