Coumarin-3-carboxylic acid chloride

Base Information

Chemical Name:Coumarin-3-carboxylic acid chloride
CAS No.:3757-06-0
Molecular Formula:C10H5ClO3
Molecular Weight:208.601
Hs Code.:2932209090
DSSTox Substance ID:DTXSID30468755
Nikkaji Number:J488.482E
Wikidata:Q82296138
Mol file:3757-06-0.mol

Synonyms:coumarin-3-carbonyl chloride

Suppliers and Price of Coumarin-3-carboxylic acid chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
2H-1-BENZOPURAN-3-CARBONYLCHLORIDE,2-OXO- 95
5g
$ 1333.00

Crysdot
2-Oxo-2H-chromene-3-carbonylchloride 97%
1g
$ 297.00

Crysdot
2-Oxo-2H-chromene-3-carbonylchloride 97%
10g
$ 1290.00

Chemenu
2-Oxo-2H-chromene-3-carbonylchloride 97%
10g
$ 1216.00

Chemenu
2-Oxo-2H-chromene-3-carbonylchloride 97%
1g
$ 281.00

Chemenu
2-Oxo-2H-chromene-3-carbonylchloride 97%
5g
$ 842.00

American Custom Chemicals Corporation
COUMARIN-3-CARBOXYLIC ACID CHLORIDE 95.00%
5G
$ 1612.96

American Custom Chemicals Corporation
COUMARIN-3-CARBOXYLIC ACID CHLORIDE 95.00%
1G
$ 945.95

Total 4 raw suppliers

Chemical Property of Coumarin-3-carboxylic acid chloride

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:369.705oC at 760 mmHg
Flash Point:171.189oC
PSA：47.28000
Density:1.477g/cm3
LogP:2.17200
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:207.9927217
Heavy Atom Count:14
Complexity:309

Purity/Quality:

95% ^*data from raw suppliers

2H-1-BENZOPURAN-3-CARBONYLCHLORIDE,2-OXO- 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(C(=O)O2)C(=O)Cl

Technology Process of Coumarin-3-carboxylic acid chloride

There total 10 articles about Coumarin-3-carboxylic acid chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 531-81-7
2-oxo-2H-chromene-3-carboxylic acid

: 3757-06-0
coumarin 3-carboxylic acid chloride

Guidance literature:: With thionyl chloride; at 80 ℃; for 4h;
DOI:10.1080/14756366.2017.1354857

Reference yield: 90.0%

: 3757-06-0
coumarin 3-carboxylic acid chloride

Guidance literature:

Reference yield:

: 1846-76-0
ethyl coumarin-3-carboxylate

: 3757-06-0
coumarin 3-carboxylic acid chloride

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH; H₂O / ethanol / Heating

2: SOCl₂

With sodium hydroxide; thionyl chloride; water; In ethanol;
DOI:10.1016/j.saa.2006.12.052