1,2-Cyclopentanedicarboxylic acid, 4-methylene-, dimethyl ester, trans-

Base Information

Chemical Name:1,2-Cyclopentanedicarboxylic acid, 4-methylene-, dimethyl ester, trans-
CAS No.:37575-81-8
Molecular Formula:C10H14O4
Molecular Weight:198.219
Hs Code.:
Mol file:37575-81-8.mol

Synonyms:

Suppliers and Price of 1,2-Cyclopentanedicarboxylic acid, 4-methylene-, dimethyl ester, trans-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,2-Cyclopentanedicarboxylic acid, 4-methylene-, dimethyl ester, trans-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,2-Cyclopentanedicarboxylic acid, 4-methylene-, dimethyl ester, trans-

There total 1 articles about 1,2-Cyclopentanedicarboxylic acid, 4-methylene-, dimethyl ester, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.8%

: 624-48-6
dimethyl cis-but-2-ene-1,4-dioate

: 6142-73-0
methylene cyclopropane

: 37745-07-6
5-methylenespiro<2.4>heptane

: 37589-17-6
methyl cis-2-(methoxycarbonyl)-4-methylenecyclopentane-1-carboxylate

: 37575-81-8
methyl trans-2-(methoxycarbonyl)-4-methylenecyclopentane-1-carboxylate

: 624-49-7
dimethylfumarate

Guidance literature:: With diethyl(ethoxy)aluminum; tris(1-methylethyl)phosphine; palladium(II) acetylacetonate; In toluene; at 100 ℃; for 16h;

Reference yield:

: 37575-81-8
methyl trans-2-(methoxycarbonyl)-4-methylenecyclopentane-1-carboxylate

: C₃₀H₄₀N₂O₄

Guidance literature:: Multi-step reaction with 17 steps

1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 0 - 20 °C

2: 1H-imidazole / N,N-dimethyl-formamide / 5.5 h / 20 °C

3: sodium hydroxide / tetrahydrofuran; methanol / 20 °C

4: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / chloroform / 20 °C

5: sodium hydroxide / tetrahydrofuran; methanol / 20 - 75 °C

6: toluene / 120 °C

7: diisobutylaluminium hydride / tetrahydrofuran / -78 - 0 °C

8: n-butyllithium / tetrahydrofuran / -78 - 0 °C

9: sodium hydrogencarbonate; Dess-Martin periodane / chloroform

10: sodium carbonate / ethanol / 1.5 h / 80 °C

11: Iodine monochloride / dichloromethane / 2 h / 0 - 20 °C

12: potassium phosphate / bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide; water / 80 °C

13: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 0.67 h / 0 - 70 °C

14: sodium hypochlorite; sodium chlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / acetonitrile; water / 1.67 h / 20 °C / Phosphate buffer

15: potassium carbonate / N,N-dimethyl-formamide / 1.33 h / 20 °C

16: trifluoroacetic acid / chloroform / 2.67 h / 20 - 50 °C

17: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 °C

With 1H-imidazole; sodium hypochlorite; sodium chlorite; potassium phosphate; n-butyllithium; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrabutyl ammonium fluoride; Iodine monochloride; diisobutylaluminium hydride; sodium hydrogencarbonate; sodium carbonate; potassium carbonate; benzotriazol-1-ol; Dess-Martin periodane; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; 9-bora-bicyclo[3.3.1]nonane; trifluoroacetic acid; sodium hydroxide; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform; water; N,N-dimethyl-formamide; toluene; acetonitrile;

Reference yield:

: 37575-81-8
methyl trans-2-(methoxycarbonyl)-4-methylenecyclopentane-1-carboxylate

: C₄₁H₅₇NO₄Si

Guidance literature:: Multi-step reaction with 12 steps

1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 0 - 20 °C

2: 1H-imidazole / N,N-dimethyl-formamide / 5.5 h / 20 °C

3: sodium hydroxide / tetrahydrofuran; methanol / 20 °C

4: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / chloroform / 20 °C

5: sodium hydroxide / tetrahydrofuran; methanol / 20 - 75 °C

6: toluene / 120 °C

7: diisobutylaluminium hydride / tetrahydrofuran / -78 - 0 °C

8: n-butyllithium / tetrahydrofuran / -78 - 0 °C

9: sodium hydrogencarbonate; Dess-Martin periodane / chloroform

10: sodium carbonate / ethanol / 1.5 h / 80 °C

11: Iodine monochloride / dichloromethane / 2 h / 0 - 20 °C

12: potassium phosphate / bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide; water / 80 °C

With 1H-imidazole; potassium phosphate; n-butyllithium; Iodine monochloride; diisobutylaluminium hydride; sodium hydrogencarbonate; sodium carbonate; Dess-Martin periodane; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; 9-bora-bicyclo[3.3.1]nonane; sodium hydroxide; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform; water; N,N-dimethyl-formamide; toluene;