Spiro[3.4]octan-1-one

Base Information

• Chemical Name: Spiro[3.4]octan-1-one
• CAS No.: 37609-31-7
• Molecular Formula: C8H12O
• Molecular Weight: 124.18000
• Hs Code.: 2914299000
• European Community (EC) Number: 874-236-5
• DSSTox Substance ID: DTXSID10501891
• Mol file: 37609-31-7.mol

Synonyms:SPIRO[3.4]OCTAN-1-ONE;37609-31-7;spiro[3.4]octan-3-one;MFCD18910992;spirooctanone;DTXSID10501891;AKOS023808473;AS-42430;SY158982;CS-0067367;EN300-170285;Z1222425050

Chemical Property of Spiro[3.4]octan-1-one

Chemical Property:

• PSA: 17.07000
• LogP: 1.90970
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 124.088815002
• Heavy Atom Count: 9
• Complexity: 143

Purity/Quality:

97% ^*data from raw suppliers

Spiro[3.4]octan-1-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC2(C1)CCC2=O

Technology Process of Spiro[3.4]octan-1-one

There total 11 articles about Spiro[3.4]octan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Cyclopropylidene cyclopentane (14949-48-5) → spiro[3.4]octan-5-one (37609-31-7)

Guidance literature:

With Eosin Y; oxygen; In pyridine; acetone; at 3 ℃; Irradiation;

DOI:10.1016/0040-4020(76)88022-2

Reference yield:

1-(1-(trimethylsiloxy)cyclopropyl)cyclopentene (39834-22-5) → spiro[3.4]octan-5-one (37609-31-7)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran;

DOI:10.1016/S0040-4039(01)91899-4

Reference yield:

Cyclopropylidene cyclopentane (14949-48-5) → 1-oxa-spiro[4.4]nonan-4-one (68978-78-9) + spiro[3.4]octan-5-one (37609-31-7) + 1-(1-Methoxy-cyclopentyl)-cyclopropanol + 1,2-dioxane-3-spirocyclopentan-4-one

Guidance literature:

With ozone; In methanol; at -78 ℃; for 0.166667h;

upstream raw materials:

Cyclopropylidene cyclopentane

1-(1-(trimethylsiloxy)cyclopropyl)cyclopentene

cyclopropyldiphenylsulfonium tetrafluoroborate

cyclopentanone

Downstream raw materials:

2-oxo-1-azaspiro<4.4>nonane

spiro[3.4]octane