1-(4-Methyl-benzyl)-1H-benzoimidazol-2-ylamine

Base Information

Chemical Name:1-(4-Methyl-benzyl)-1H-benzoimidazol-2-ylamine
CAS No.:37743-74-1
Molecular Formula:C15H15N3
Molecular Weight:237.304
Hs Code.:
DSSTox Substance ID:DTXSID60357764
Nikkaji Number:J468.061H
Wikidata:Q82137844
ChEMBL ID:CHEMBL1556779

Synonyms:37743-74-1;1-(4-Methyl-benzyl)-1H-benzoimidazol-2-ylamine;1-(4-Methylbenzyl)-1H-benzo[d]imidazol-2-amine;1-(4-methylbenzyl)-1H-benzimidazol-2-amine;1-[(4-methylphenyl)methyl]-1h-1,3-benzodiazol-2-amine;Enamine_000687;Oprea1_093883;Oprea1_676304;MLS001208029;CHEMBL1556779;DTXSID60357764;HMS1395P05;CCG-16981;STL296092;AKOS000559978;SMR000514788;CS-0327521;EU-0038896;1-(4-methylbenzyl)-1h-benzoimidazol-2-ylamine;AB00092124-01;1-(4-methylbenzyl)-1h-benzo[d]imidazol-2-ylamine

Suppliers and Price of 1-(4-Methyl-benzyl)-1H-benzoimidazol-2-ylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(4-Methylbenzyl)-1H-benzo[d]imidazol-2-amine 97%
1g
$ 550.00

Total 4 raw suppliers

Chemical Property of 1-(4-Methyl-benzyl)-1H-benzoimidazol-2-ylamine

Chemical Property:

Boiling Point:462.0±48.0 °C(Predicted)
PSA：44.57000
Density:1.18±0.1 g/cm3(Predicted)
LogP:2.90530
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:237.126597491
Heavy Atom Count:18
Complexity:273

Purity/Quality:

99% ^*data from raw suppliers

1-(4-Methylbenzyl)-1H-benzo[d]imidazol-2-amine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)CN2C3=CC=CC=C3N=C2N
Uses 2-Amino-1-(4-methylbenzyl)benzimidazole is an intermediate in the synthesis of Yan 7874 (Y100510) which is a potential drug in the treatment of narcolepsy, insomnia and maybe other sleep and vigilance disorders. Yan 7874 is a orexin 2 receptor agonist, yet the efficacy of Yan 7874 also appears weak, and should also be clearly improved to make it useful as a drug or research tool.

Technology Process of 1-(4-Methyl-benzyl)-1H-benzoimidazol-2-ylamine

There total 5 articles about 1-(4-Methyl-benzyl)-1H-benzoimidazol-2-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.4%