4-Chloro-6-phenylquinoline

Base Information

Chemical Name:4-Chloro-6-phenylquinoline
CAS No.:5443-23-2
Molecular Formula:C15H10ClN
Molecular Weight:239.704
Hs Code.:
NSC Number:12826
DSSTox Substance ID:DTXSID00279491
Nikkaji Number:J3.500.676A
Wikidata:Q82012111

Synonyms:4-chloro-6-phenylquinoline;5443-23-2;NSC12826;DTXSID00279491;NSC 12826;NSC-12826;AKOS005842390;J3.500.676A

Suppliers and Price of 4-Chloro-6-phenylquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 4-Chloro-6-phenylquinoline

Chemical Property:

Vapor Pressure:1.53E-05mmHg at 25°C
Boiling Point:376.8°C at 760 mmHg
Flash Point:213.5°C
Density:1.235g/cm³
XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:239.0501770
Heavy Atom Count:17
Complexity:249

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC3=C(C=CN=C3C=C2)Cl

Technology Process of 4-Chloro-6-phenylquinoline

There total 4 articles about 4-Chloro-6-phenylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 65340-70-7
6-bromo-4-chloroquinoline

: 24388-23-6
2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole

: 5443-23-2
4-chloro-6-phenylquinoline

Guidance literature:: With sodium carbonate; In water; at 120 ℃; for 0.5h; Irradiation;
DOI:10.1039/c5ob01915j

Reference yield:

: 65340-70-7
6-bromo-4-chloroquinoline

: 98-80-6
phenylboronic acid

: 5443-23-2
4-chloro-6-phenylquinoline

Guidance literature:: With palladium bis[bis(diphenylphosphino)ferrocene] dichloride; sodium carbonate; In ethanol; toluene; at 120 ℃;
DOI:10.1016/j.bmcl.2010.06.107

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 5443-23-2
4-chloro-6-phenylquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium acetate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 0.75 h / 120 °C / Irradiation

2: sodium carbonate / water / 0.5 h / 120 °C / Irradiation

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium acetate; sodium carbonate; In 1,4-dioxane; water; 1: |Suzuki-Miyaura Coupling;
DOI:10.1039/c5ob01915j