N-[(4-fluorophenyl)methyl]-2-oxo-1,3-dihydroindole-5-sulfonamide

Base Information

Chemical Name:N-[(4-fluorophenyl)methyl]-2-oxo-1,3-dihydroindole-5-sulfonamide
CAS No.:380242-04-6
Molecular Formula:C15H13FN2O3S
Molecular Weight:320.344
Hs Code.:
DSSTox Substance ID:DTXSID401326994
ChEMBL ID:CHEMBL1878527

Synonyms:MLS002156925;SCHEMBL5840708;CHEMBL1878527;IEJOUCFNOKPSPG-UHFFFAOYSA-N;DTXSID401326994;HMS3089O06;N-[(4-fluorophenyl)methyl]-2-oxo-1,3-dihydroindole-5-sulfonamide;AKOS016597448;SMR000844281;Z90683476;2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid 4-fluoro-benzylamide;2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid-4-fluoro-benzylamide;380242-04-6

Suppliers and Price of N-[(4-fluorophenyl)methyl]-2-oxo-1,3-dihydroindole-5-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-[(4-fluorophenyl)methyl]-2-oxo-1,3-dihydroindole-5-sulfonamide

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:320.06309162
Heavy Atom Count:22
Complexity:511

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C2=C(C=CC(=C2)S(=O)(=O)NCC3=CC=C(C=C3)F)NC1=O

Technology Process of N-[(4-fluorophenyl)methyl]-2-oxo-1,3-dihydroindole-5-sulfonamide

There total 2 articles about N-[(4-fluorophenyl)methyl]-2-oxo-1,3-dihydroindole-5-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 140-75-0
para-fluorobenzylamine

: 199328-31-9
2-oxo-2,3-dihydro-1H-indole-5-sulfonyl chloride

: 380242-04-6
2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid-4-fluoro-benzylamide

Guidance literature:: In tetrahydrofuran; at 20 ℃;
DOI:10.1016/j.bmcl.2003.09.069

Reference yield:

: 59-48-3
2-oxoindole

: 380242-04-6
2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid-4-fluoro-benzylamide

Guidance literature:: Multi-step reaction with 2 steps

1: ClSO₃H / 0 °C

2: tetrahydrofuran / 20 °C

With chlorosulfonic acid; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2003.09.069