5-BROMO-2-(1H-TETRAZOL-5-YL)PYRIDINE

Base Information

• Chemical Name: 5-BROMO-2-(1H-TETRAZOL-5-YL)PYRIDINE
• CAS No.: 380380-60-9
• Molecular Formula: C6H4BrN5
• Molecular Weight: 226.03
• Hs Code.: 2933990090
• Mol file: 380380-60-9.mol

Synonyms:5-BROMO-2-(1H-TETRAZOL-5-YL)PYRIDINE;Pyridine, 5-broMo-2-(2H-tetrazol-5-yl)-;5-broMo-2-(2H-tetrazol-5-yl)pyridine;Tedizolid interMediate E;5-Bromo-2-(tetrazol-5-yl)pyridine

Chemical Property of 5-BROMO-2-(1H-TETRAZOL-5-YL)PYRIDINE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.665
• Boiling Point: 396.451 °C at 760 mmHg
• PKA: 4.29±0.29(Predicted)
• Flash Point: 193.567 °C
• PSA: 67.35000
• Density: 1.851 g/cm³
• LogP: 1.02420
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-2-(1H-tetrazol-5-yl)pyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-Bromo-2-(1H-tetrazol-5-yl)pyridine is a reagent in the synthesis and antibacterial activity of oxazolidinones containing pyridine substituted with heteroaromatic ring.

Technology Process of 5-BROMO-2-(1H-TETRAZOL-5-YL)PYRIDINE

There total 5 articles about 5-BROMO-2-(1H-TETRAZOL-5-YL)PYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.8%

2-Cyano-5-bromopyridine (97483-77-7) → 5-bromo-2-(2H-tetrazol-5-yl)pyridine (380380-60-9)

Guidance literature:

With pyridine; Caswell No_. 744A; anhydrous zinc chloride; at 40 - 120 ℃; for 2h;

Reference yield: 89.0%

C6H7BrN4 → 5-bromo-2-(2H-tetrazol-5-yl)pyridine (380380-60-9)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water; at -5 - 10 ℃; for 0.5h; Temperature;

Reference yield: 85.0%

2-Cyano-5-bromopyridine (97483-77-7) → 2-(1,2,3,4-tetrazol-5-yl)-5-bromopyridine (380380-60-9)

Guidance literature:

With sodium azide; ammonium chloride; In DMF (N,N-dimethyl-formamide); at 20 - 110 ℃; for 3h;

upstream raw materials:

2-Cyano-5-bromopyridine

2,5-dibromopyridine

Downstream raw materials:

(S)-[N-3-(4-(2-(5-methyl-(1,3,4)-oxadiazol-2-yl)-pyrid in-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

5-bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine

2-(1-methyl-1,2,3,4-tetrazol-5-yl)-5-bromopyridine

2-(1-methyl-1H-tetrazol-5-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine