Macimorelin

Base Information

• Chemical Name: Macimorelin
• CAS No.: 381231-18-1
• Molecular Formula: C26H30N6O3
• Molecular Weight: 474.55500
• UNII: 8680B21W73
• DSSTox Substance ID: DTXSID601045766
• Wikipedia: Macimorelin
• Wikidata: Q15624037
• NCI Thesaurus Code: C95123
• RXCUI: 1999420
• Pharos Ligand ID: 489Z6162AXTR,WKLJUH1DL7ZN
• Metabolomics Workbench ID: 153944
• ChEMBL ID: CHEMBL278623
• Mol file: 381231-18-1.mol

Synonyms:AEZS-130;Aib-DTrp-DgTrp-CHO;Aib-Trp-gTrp-CHO;aminoisobutyryl-tryptophyl-tryptophanamine-formyl;ARD-07;EP 1572;EP-1572;EP1572;JMV 1843;JMV-1843;JMV1843;macimorelin;macimorelin acetate;Macrilen

Chemical Property of Macimorelin

Chemical Property:

• Appearance/Colour: White to Off-White Powder
• Boiling Point: 948.6±65.0 °C(Predicted)
• PKA: 14.73±0.23(Predicted)
• PSA: 144.90000
• Density: 1.309±0.06 g/cm3(Predicted)
• LogP: 4.35370
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 474.23793884
• Heavy Atom Count: 35
• Complexity: 761

Purity/Quality:

99% ^*data from raw suppliers

ARD-07 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC3=CNC4=CC=CC=C43)NC=O)N
• Isomeric SMILES: CC(C)(C(=O)N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@H](CC3=CNC4=CC=CC=C43)NC=O)N
• Recent ClinicalTrials: A Research Study of How Well Macimorelin Works to Find Out if Children Have a Lack of Growth Hormone and How Safe it is
• Recent EU Clinical Trials: Multicenter, open label trial to investigate the efficacy and safety of a single oral dose of 1.0 mg/kg macimorelin acetate as growth hormone stimulation test (GHST) in pediatric patients with suspected growth hormone deficiency (GHD)