2-(4-Hydroxy-phenyl)-1h-quinolin-4-one

Base Information

Chemical Name:2-(4-Hydroxy-phenyl)-1h-quinolin-4-one
CAS No.:3813-93-2
Molecular Formula:C15H11NO2
Molecular Weight:237.258
Hs Code.:2933499090
ChEMBL ID:CHEMBL2030006
DSSTox Substance ID:DTXSID10469725
Mol file:3813-93-2.mol

Synonyms:3813-93-2;2-(4-hydroxy-phenyl)-1h-quinolin-4-one;2-(4-hydroxyphenyl)-1H-quinolin-4-one;2-(4-Hydroxyphenyl)-1H-4-quinolinone;SCHEMBL311524;CHEMBL2030006;DTXSID10469725;NFHVMJUQDROCSJ-UHFFFAOYSA-N

Suppliers and Price of 2-(4-Hydroxy-phenyl)-1h-quinolin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(4-HYDROXYPHENYL)-1H-4-QUINOLINONE 95.00%
1G
$ 952.01

Total 5 raw suppliers

Chemical Property of 2-(4-Hydroxy-phenyl)-1h-quinolin-4-one

Chemical Property:

PSA：53.09000
LogP:2.90070
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:237.078978594
Heavy Atom Count:18
Complexity:356

Purity/Quality:

97% ^*data from raw suppliers

2-(4-HYDROXYPHENYL)-1H-4-QUINOLINONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)C=C(N2)C3=CC=C(C=C3)O

Technology Process of 2-(4-Hydroxy-phenyl)-1h-quinolin-4-one

There total 5 articles about 2-(4-Hydroxy-phenyl)-1h-quinolin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 884501-91-1
C₁₆H₁₅NO₃

: 3813-93-2
2-(4-hydroxy-phenyl)-1H-quinolin-4-one

Guidance literature:: With hydrogen bromide; In water; for 16h; Heating / reflux;

Reference yield: 58.0%

: 1361006-01-0
(E)-ethyl 3-(4-hydroxyphenyl)-3-(phenylamino)acrylate

: 3813-93-2
2-(4-hydroxy-phenyl)-1H-quinolin-4-one

Guidance literature:: With diphenyl ether-biphenyl eutectic; at 240 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/jm201179h

Reference yield:

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 3813-93-2
2-(4-hydroxy-phenyl)-1H-quinolin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: niobium pentachloride / dichloromethane / 48 h / 20 °C / Inert atmosphere

2: acetic acid / ethanol / Inert atmosphere; Reflux

3: diphenyl ether-biphenyl eutectic / 0.5 h / 240 °C / Inert atmosphere

With diphenyl ether-biphenyl eutectic; niobium pentachloride; acetic acid; In ethanol; dichloromethane;
DOI:10.1021/jm201179h