Acetamide, N-(2-ethynylphenyl)-N-2-propenyl-

Base Information

Chemical Name:Acetamide, N-(2-ethynylphenyl)-N-2-propenyl-
CAS No.:382156-92-5
Molecular Formula:C13H13NO
Molecular Weight:199.252
Hs Code.:
DSSTox Substance ID:DTXSID70460859
Nikkaji Number:J1.818.620I
Wikidata:Q82285016
Mol file:382156-92-5.mol

Synonyms:Acetamide, N-(2-ethynylphenyl)-N-2-propenyl-;382156-92-5;DTXSID70460859

Suppliers and Price of Acetamide, N-(2-ethynylphenyl)-N-2-propenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetamide, N-(2-ethynylphenyl)-N-2-propenyl-

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:199.099714038
Heavy Atom Count:15
Complexity:286

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N(CC=C)C1=CC=CC=C1C#C

Technology Process of Acetamide, N-(2-ethynylphenyl)-N-2-propenyl-

There total 3 articles about Acetamide, N-(2-ethynylphenyl)-N-2-propenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 110598-59-9
N-acetyl-2-<(trimethylsilyl)ethynyl>aniline

: 106-95-6
allyl bromide

: 382156-92-5
N-(2-ethynylphenyl)-N-(prop-2-enyl)acetamide

Guidance literature:: With potassium hydroxide; tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; for 5h; sonication;
DOI:10.1002/1522-2675(200209)85:9<2856::AID-HLCA2856>3.0.CO;2-5

Reference yield:

: 615-43-0
2-iodophenylamine

: 382156-92-5
N-(2-ethynylphenyl)-N-(prop-2-enyl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / Pd(PPh₃)2Cl₂; CuI / triethylamine / 5 h / 60 °C

2: 88 percent / Et₃N / diethyl ether / 1 h / 0 °C

3: 98 percent / KOH; Bu₄NI / tetrahydrofuran / 5 h / sonication

With potassium hydroxide; tetra-(n-butyl)ammonium iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In tetrahydrofuran; diethyl ether; triethylamine;
DOI:10.1002/1522-2675(200209)85:9<2856::AID-HLCA2856>3.0.CO;2-5

Reference yield:

: 103529-16-4
2-[(trimethylsilyl)ethynyl]aniline

: 382156-92-5
N-(2-ethynylphenyl)-N-(prop-2-enyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / Et₃N / diethyl ether / 1 h / 0 °C

2: 98 percent / KOH; Bu₄NI / tetrahydrofuran / 5 h / sonication

With potassium hydroxide; tetra-(n-butyl)ammonium iodide; triethylamine; In tetrahydrofuran; diethyl ether;
DOI:10.1002/1522-2675(200209)85:9<2856::AID-HLCA2856>3.0.CO;2-5