2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-3-PHENYLPROPANOIC ACID

Base Information

Chemical Name:2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-3-PHENYLPROPANOIC ACID
CAS No.:38229-08-2
Molecular Formula:C₁₇H₁₃NO₄
Molecular Weight:295.295
Hs Code.:
Mol file:38229-08-2.mol

Synonyms:(R)-N-phthaloylphenylalanine;N,N-phthaloyl-D-phenylalanine;METHYL 2-(1,3-DIOXOISOINDOL-2-YL)-3-PHENYL-PROPANOATE;methyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoate;N,N-Phthaloyl-D-phenylalanin;2h-isoindole-2-acetic acid,1,3-dihydro-1,3-dioxo-|A-(phenylmethyl)-,methyl ester;N,N-Phthaloyl-DL-phenylalanin-methylester;methyl 2-(1,3-dioxoisoindolin-2-yl)-3-phenylpropanoate;N-phthalyl-D-phenylalanine;N-phthaloyl-(R)-phenylalanine;(R)-2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionic acid;N,N-phthaloyl-DL-phenylalanine-methyl ester;

Suppliers and Price of 2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-3-PHENYLPROPANOIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
N-PHTHALOYL-DL-PHENYLALANINE AldrichCPR
250mg
$ 33.40

American Custom Chemicals Corporation
2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-3-PHENYLPROPANOIC ACID 95.00%
5G
$ 1005.43

American Custom Chemicals Corporation
2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-3-PHENYLPROPANOIC ACID 95.00%
2.5G
$ 852.21

American Custom Chemicals Corporation
2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-3-PHENYLPROPANOIC ACID 95.00%
1G
$ 648.81

Total 3 raw suppliers

Chemical Property of 2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-3-PHENYLPROPANOIC ACID

Chemical Property:

Vapor Pressure:9.78E-11mmHg at 25°C
Melting Point:185 - 186.5 °C (H2O)
PSA：74.68000
LogP:1.91640

Purity/Quality:

99% ^*data from raw suppliers

N-PHTHALOYL-DL-PHENYLALANINE AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-3-PHENYLPROPANOIC ACID

There total 7 articles about 2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-3-PHENYLPROPANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 85-44-9
phthalic anhydride

: 673-06-3,25191-15-5,658-69-5,67675-33-6
D-(R)-phenylalanine

: 3588-64-5,5123-55-7,32150-90-6,38229-08-2
(R)-2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionic acid

Guidance literature:: for 0.05h; microwave irradiation;

Reference yield: 100.0%

: 1242459-38-6
C₂₃H₂₉NO₄Si₂

: 3588-64-5,5123-55-7,32150-90-6,38229-08-2
(R)-2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionic acid

Guidance literature:: With 2,6-di-tert-butyl-pyridine; 2.6-dimethylphenol; C₃₂H₁₂BF₂₄^(1-)*C₄₄H₃₀N₂O₂P⁽¹⁺⁾; In toluene; at -20 ℃; for 20h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ja105945z