Bipolaramide

Base Information

Chemical Name:Bipolaramide
CAS No.:82220-76-6
Molecular Formula:C₁₈H₁₄N₂O₄
Molecular Weight:322.32
Hs Code.:
UNII:EU3A52R27S
Nikkaji Number:J91.886E
Wikidata:Q105019168
Mol file:82220-76-6.mol

Synonyms:Bipolaramide;(-)-Bipolaramide;EU3A52R27S;UNII-EU3A52R27S;82220-76-6;6H,13H-Pyrazino(1,2-a:4,5-a')diindole-6,13-dione, 6a,7,13a,14-tetrahydro-4,11-dihydroxy-, (6aS,13aS)-;6H,13H-Pyrazino(1,2-a:4,5-a')diindole-6,13-dione, 6a,7,13a,14-tetrahydro-4,11-dihydroxy-, (6as-cis)-

Suppliers and Price of Bipolaramide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Bipolaramide

Chemical Property:

Melting Point:299 - 301 °C
PSA：81.08000
LogP:1.45700
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:322.09535693
Heavy Atom Count:24
Complexity:531

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C2C(=O)N3C(CC4=C3C(=CC=C4)O)C(=O)N2C5=C1C=CC=C5O
Isomeric SMILES:C1[C@H]2C(=O)N3[C@@H](CC4=C3C(=CC=C4)O)C(=O)N2C5=C1C=CC=C5O

Technology Process of Bipolaramide

There total 3 articles about Bipolaramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

: (6aS-cis)-4,11-di-6a,7,13a,14-tetrahydropyrazino<1,2-a:4,5-a'>diindole-6,13-dione

: 82220-76-6
bipolaramide

: 128562-37-8
(6aS-cis)-4-hydroxy-6a,7,13a,14-tetrahydropyrazino<1,2-a:4,5-a'>diindole-6,13-dione

Guidance literature:: With copper(II) sulfate; In water; N,N-dimethyl-formamide; at 132 ℃; for 3h;
DOI:10.3987/COM-95-S21

Reference yield:

: 104321-36-0
(6aS-cis)-6a,7,13a,14-tetrahydropyrazino<1,2-a:4,5-a'>diindole-6,13-dione

: 82220-76-6
bipolaramide

: 128562-37-8
(6aS-cis)-4-hydroxy-6a,7,13a,14-tetrahydropyrazino<1,2-a:4,5-a'>diindole-6,13-dione

Guidance literature:: With copper(II) sulfate; thallium(III) trifluoroacetate; Yield given. Multistep reaction. Yields of byproduct given; 1.) trifluoroacetic acid, room temperature, 24 h, 2.) N,N-dimethylformamide, water, 132 deg C, 3 h;
DOI:10.1248/cpb.37.3426

Reference yield:

: Thallium tris(trifluoroacetate)

: 104321-36-0
(6aS-cis)-6a,7,13a,14-tetrahydropyrazino<1,2-a:4,5-a'>diindole-6,13-dione

: 82220-76-6
bipolaramide

: 128562-37-8
(6aS-cis)-4-hydroxy-6a,7,13a,14-tetrahydropyrazino<1,2-a:4,5-a'>diindole-6,13-dione

Guidance literature:: With copper(II) sulfate; Yield given. Multistep reaction. Yields of byproduct given; 1.) TFA, room t., 12 h; 2.) DMF, 135 degC, 3 h;
DOI:10.3987/COM-95-S21