Phosphonic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenylmethyl]-, diethyl ester

Base Information

• Chemical Name: Phosphonic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenylmethyl]-, diethyl ester
• CAS No.: 38428-06-7
• Molecular Formula: C19H20NO5P
• Molecular Weight: 373.345

Synonyms:[(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-phenyl-methyl]-phosphonic acid diethyl ester;

Chemical Property of Phosphonic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenylmethyl]-, diethyl ester

Chemical Property:

• Melting Point: 102 - 103 °C
• Boiling Point: 518.3±50.0 °C(Predicted)
• PSA: 82.72000
• Density: 1.312±0.06 g/cm3(Predicted)
• LogP: 4.18540

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of Phosphonic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenylmethyl]-, diethyl ester

There total 2 articles about Phosphonic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenylmethyl]-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(phthalimido)phenylmethyltris(4-trifluoromethylphenyl)phosphonium tetrafluoroborate + triethyl phosphite (122-52-1) → diethyl phenyl(N-phthalimido)methylphosphonate (38428-06-7)

Guidance literature:

With methyl-triphenylphosphonium iodide; In chloroform; at 80 ℃; for 0.5h; Reagent/catalyst; Sealed tube;

DOI:10.3390/molecules24183405

Reference yield:

→ diethyl phenyl(N-phthalimido)methylphosphonate (38428-06-7)

Guidance literature:

Phosphonate II, Phthalsaeureanhydrid;

DOI:10.1246/bcsj.45.2528

upstream raw materials:

triethyl phosphite

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