Phosphonic dichloride, 2-pyridinyl- (9CI)

Base Information

• Chemical Name: Phosphonic dichloride, 2-pyridinyl- (9CI)
• CAS No.: 38606-04-1
• Molecular Formula: C5H4Cl2NOP
• Molecular Weight: 195.97100
• Hs Code.: 2933399090
• Mol file: 38606-04-1.mol

Synonyms:2-Pyridylphosphonsaeuredichlorid;Phosphonic dichloride,2-pyridinyl;

Chemical Property of Phosphonic dichloride, 2-pyridinyl- (9CI)

Chemical Property:

• PSA: 39.77000
• LogP: 2.37760

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phosphonic dichloride, 2-pyridinyl- (9CI)

There total 1 articles about Phosphonic dichloride, 2-pyridinyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-Pyridylphosphonsaeuredichlorid (38606-04-1)

Guidance literature:

DOI:10.1007/BF00470159 DOI:10.1021/jo00947a012

Reference yield: 24.0%

2-Pyridylphosphonsaeuredichlorid (38606-04-1) + (S)-1-phenyl-2,2,3-trimethylbutane-1,3-diol → 2-((2R,6R)-4,4,5,5-Tetramethyl-2-oxo-6-phenyl-2λ5-[1,3,2]dioxaphosphinan-2-yl)-pyridine

Guidance literature:

With triethylamine; In chloroform; at 0 ℃;

DOI:10.1016/S0040-4020(98)00414-1

Reference yield: 24.0%

(S)-(+)-1-phenyl-2,2-dimethyl-1,3-propanediol (52178-66-2,98674-79-4) + 2-Pyridylphosphonsaeuredichlorid (38606-04-1) → 2-((2S,4R)-5,5-Dimethyl-2-oxo-4-phenyl-2λ5-[1,3,2]dioxaphosphinan-2-yl)-pyridine (210910-05-7) + 2-((2R,4R)-5,5-Dimethyl-2-oxo-4-phenyl-2λ5-[1,3,2]dioxaphosphinan-2-yl)-pyridine (210910-04-6)

Guidance literature:

With triethylamine; In chloroform; Ambient temperature;

DOI:10.1016/S0040-4020(98)00414-1

Downstream raw materials:

2-((2S,4R)-5,5-Dimethyl-2-oxo-4-phenyl-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-pyridine

2-((2R,4R)-5,5-Dimethyl-2-oxo-4-phenyl-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-pyridine