17-OXODEXAMETHASONE

Base Information

• Chemical Name: 17-OXODEXAMETHASONE
• CAS No.: 1880-61-1
• Molecular Formula: C₂₀H₂₅FO₃
• Molecular Weight: 332.415
• Mol file: 1880-61-1.mol

Synonyms:Androsta-1,4-diene-3,17-dione,9-fluoro-11b-hydroxy-16a-methyl- (7CI,8CI); 9-Fluoro-11b-hydroxy-16a-methylandrosta-1,4-diene-3,17-dione;9a-Fluoro-11b-hydroxy-16a-methylandrosta-1,4-diene-3,17-dione;NSC 50909

Chemical Property of 17-OXODEXAMETHASONE

Chemical Property:

• Vapor Pressure: 3.54E-11mmHg at 25°C
• Melting Point: 242-244°C
• Boiling Point: 478.8°Cat760mmHg
• PKA: 13.23±0.70(Predicted)
• Flash Point: 243.4°C
• PSA: 54.37000
• Density: 1.23g/cm³
• LogP: 3.17230
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly), Ethanol (Slightly), Methanol (S

Purity/Quality:

98%,99%, ^*data from raw suppliers

17-OxoDexamethasone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite of Dexamethasone A metabolite of Dexamethasone.

Technology Process of 17-OXODEXAMETHASONE

There total 5 articles about 17-OXODEXAMETHASONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 3.2%

17β-(2-aminooxazol-4-yl)-9α-fluoro-11β,17α-dihydroxy-16α-methylandrosta-1,4-dien-3-one (99646-91-0) → 9α-fluoro-androsta-1,4-diene-11β-hydroxy-16α-methyl-3,17-dione (1880-61-1) + 9-fluoro-11β,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17-carboxamid (82137-90-4) + C22H26FNO5 (105394-99-8) + N-(aminocarbonyl)-9-fluoro-11β,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17-carboxamid (105360-82-5)

Guidance literature:

With dihydrogen peroxide; In methanol; for 216h; Ambient temperature;

DOI:10.1016/0039-128X(85)90030-3

Reference yield:

→ 9α-fluoro-11β-hydroxy-16α-methylandrosta-1,4-diene-3,17-dione (1880-61-1,2285-53-2,3109-01-1)

Guidance literature:

11β,17α-Dihydroxy-9α-fluor-16α-methyl-pregna-1,4-dien-3,20-dion;

Reference yield:

→ (9R,10S,11S,13S)-9-Fluoro-11-hydroxy-10,13,16-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-6H-cyclopenta[a]phenanthrene-3,17-dione (1880-61-1,2285-53-2,3109-01-1)

Guidance literature:

Androstadien-dion IIa, Epimerisierung;

DOI:10.1002/jps.2600680508

upstream raw materials:

17β-(2-aminooxazol-4-yl)-9α-fluoro-11β,17α-dihydroxy-16α-methylandrosta-1,4-dien-3-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1880-61-1 17-OXODEXAMETHASONE

Send

Send

Metric Ton KG G Pound L ML

Send

Send