4-Amino-3-hydroxybutanamide

Base Information

• Chemical Name: 4-Amino-3-hydroxybutanamide
• CAS No.: 51499-73-1
• Molecular Formula: C4H10 N2 O2
• Molecular Weight: 118.13
• Hs Code.: 2924199090
• DSSTox Substance ID: DTXSID20965829
• Mol file: 51499-73-1.mol

Synonyms:4-amino-3-hydroxybutanamide;4-amino-3-hydroxybutanamide monohydrobromide;4-amino-3-hydroxybutanamide monohydrochloride

Chemical Property of 4-Amino-3-hydroxybutanamide

Chemical Property:

• Vapor Pressure: 2.57E-09mmHg at 25°C
• Boiling Point: 433°C at 760 mmHg
• PKA: 12.44±0.35(Predicted)
• Flash Point: 215.7°C
• PSA: 90.33000
• Density: 1.218g/cm³
• LogP: 0.03140
• XLogP3: -2.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 118.074227566
• Heavy Atom Count: 8
• Complexity: 84.1

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(C(CN)O)C(=O)N

Technology Process of 4-Amino-3-hydroxybutanamide

There total 2 articles about 4-Amino-3-hydroxybutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

but-3-enoic acid (625-38-7) → γ-Amino-β-hydroxybutansaeureamid (51499-73-1)

Guidance literature:

Multistep reaction;

DOI:10.1021/ja964399w

Reference yield:

→ γ-Amino-β-hydroxybutansaeureamid (51499-73-1)

Guidance literature:

γ-Chlor-β-hydroxybutansaeureamid, NH4OH;

Reference yield: 83.0%

γ-Amino-β-hydroxybutansaeureamid (51499-73-1) + N-(benzyloxycarbonyl)-L-phenylalanine benzyl ester (60379-01-3) → [(S)-1-(3-Carbamoyl-2-hydroxy-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester

Guidance literature:

With subtilisin BPN'; triethylamine; In water; N,N-dimethyl-formamide; Ambient temperature;

DOI:10.1021/ja964399w

upstream raw materials:

but-3-enoic acid