(2E)-2-benzylidenecyclohexan-1-amine Hydrochloride

Base Information

• Chemical Name: (2E)-2-benzylidenecyclohexan-1-amine Hydrochloride
• CAS No.: 114506-91-1
• Molecular Formula: C13H17 N . Cl H
• Molecular Weight: 223.7417
• Mol file: 114506-91-1.mol

Synonyms:(2E)-2-benzylidenecyclohexan-1-amine Hydrochloride;114506-91-1

Chemical Property of (2E)-2-benzylidenecyclohexan-1-amine Hydrochloride

Chemical Property:

• Vapor Pressure: 0.00062mmHg at 25°C
• Boiling Point: 309.9°C at 760 mmHg
• Flash Point: 147.4°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 223.1127773
• Heavy Atom Count: 15
• Complexity: 201

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(=CC2=CC=CC=C2)C(C1)N.Cl
• Isomeric SMILES: C1CC/C(=C\C2=CC=CC=C2)/C(C1)N.Cl

Technology Process of (2E)-2-benzylidenecyclohexan-1-amine Hydrochloride

There total 3 articles about (2E)-2-benzylidenecyclohexan-1-amine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

(E)-2-(phenylmethylene)cyclohexanamine (105206-09-5) → (E)-2-(phenylmethylene)cyclohexanamine hydrochloride (114506-91-1)

Guidance literature:

With hydrogenchloride; In diethyl ether;

DOI:10.1021/jm00403a013

Reference yield:

(E)-2-benzylidenecyclohexanone (5682-83-7,31021-02-0,1467-15-8) → (E)-2-(phenylmethylene)cyclohexanamine hydrochloride (114506-91-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / hydroxylamine hydrochloride, aq. NaOH / ethanol / 1 h / Heating

2: zinc dust, acetic acid / ethanol / 1 h / 4 °C

3: 78 percent / HCl / diethyl ether

With hydrogenchloride; sodium hydroxide; hydroxylamine hydrochloride; acetic acid; zinc; In diethyl ether; ethanol;

DOI:10.1021/jm00403a013

Reference yield:

2-(phenylmethylene)cyclohexanone oxime (114506-90-0,35235-98-4) → (E)-2-(phenylmethylene)cyclohexanamine hydrochloride (114506-91-1)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc dust, acetic acid / ethanol / 1 h / 4 °C

2: 78 percent / HCl / diethyl ether

With hydrogenchloride; acetic acid; zinc; In diethyl ether; ethanol;

DOI:10.1021/jm00403a013

upstream raw materials:

(E)-2-(phenylmethylene)cyclohexanamine

(E)-2-benzylidenecyclohexanone

2-(phenylmethylene)cyclohexanone oxime

Refernces