5(4H)-Oxazolone, 4-[(1R,2E)-1-(acetyloxy)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-buten yl]-4-[(dimethylphenylsilyl)methyl]-2-phenyl-, (4R)-

Base Information

Chemical Name:5(4H)-Oxazolone, 4-[(1R,2E)-1-(acetyloxy)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-buten yl]-4-[(dimethylphenylsilyl)methyl]-2-phenyl-, (4R)-
CAS No.:389807-13-0
Molecular Formula:C40H45NO5Si2
Molecular Weight:675.972
Hs Code.:

5(4H)-Oxazolone,
4-[(1R,2E)-1-(acetyloxy)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-buten
yl]-4-[(dimethylphenylsilyl)methyl]-2-phenyl-, (4R)-

Synonyms:

Suppliers and Price of 5(4H)-Oxazolone, 4-[(1R,2E)-1-(acetyloxy)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-buten yl]-4-[(dimethylphenylsilyl)methyl]-2-phenyl-, (4R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5(4H)-Oxazolone, 4-[(1R,2E)-1-(acetyloxy)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-buten yl]-4-[(dimethylphenylsilyl)methyl]-2-phenyl-, (4R)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5(4H)-Oxazolone, 4-[(1R,2E)-1-(acetyloxy)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-buten yl]-4-[(dimethylphenylsilyl)methyl]-2-phenyl-, (4R)-

There total 5 articles about 5(4H)-Oxazolone, 4-[(1R,2E)-1-(acetyloxy)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-buten yl]-4-[(dimethylphenylsilyl)methyl]-2-phenyl-, (4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 169689-20-7
(E)-1,1-diacetoxy-4-(t-butyldiphenylsilyloxy)-2-butene

: 389807-44-7
2-phenyl-4-(dimethylphenylsilyl)methyl-4,5-dihydro-5-oxazolone

: 389807-13-0
(1'R,4R,2'E)-4-[1'-acetoxy-4'-(tert-butyldiphenylsilyloxy)but-2'-en-1'-yl]-4-(dimethylphenylsilyl)methyl-2-phenyl-4,5-dihydro-5-oxazolone

: 389807-11-8
(1'R,4S,2'E)-4-[1'-acetoxy-4'-(tert-butyldiphenylsilyloxy)but-2'-en-1'-yl]-4-(dimethylphenylsilyl)methyl-2-phenyl-4,5-dihydro-5-oxazolone

Guidance literature:: 2-phenyl-4-(dimethylphenylsilyl)methyl-4,5-dihydro-5-oxazolone; With sodium hydride; In tetrahydrofuran; at 25 ℃; Irradiation;

With bis(η3-allyl-μ-chloropalladium(II)); (1R,2R)-1,2-bis[(2-diphenylphosphanyl)benzoylamino]cyclohexane; In tetrahydrofuran; at 25 ℃;

(E)-1,1-diacetoxy-4-(t-butyldiphenylsilyloxy)-2-butene; In tetrahydrofuran; at 0 ℃; for 3h; Further stages.;
DOI:10.1021/ja0118338

Reference yield:

: 101649-82-5
N-benzoyl-2-bromoglycine methyl ester

: 389807-13-0
(1'R,4R,2'E)-4-[1'-acetoxy-4'-(tert-butyldiphenylsilyloxy)but-2'-en-1'-yl]-4-(dimethylphenylsilyl)methyl-2-phenyl-4,5-dihydro-5-oxazolone

Guidance literature:: Multi-step reaction with 4 steps

1.1: 61 percent / tetrahydrofuran / 3 h / -78 - 0 °C

2.1: 94 percent / LiOH / tetrahydrofuran; H₂O / 8 h / 25 °C

3.1: 97 percent / DCC / tetrahydrofuran / 12 h / 25 °C

4.1: NaH / tetrahydrofuran / 25 °C / Irradiation

4.2: (η³-C3H5PdCl)2; (R,R)-1,2-(o-PPh2-C6H4-CO-NH)2-cyclohexane / tetrahydrofuran / 25 °C

4.3: 23 percent / tetrahydrofuran / 3 h / 0 °C

With lithium hydroxide; sodium hydride; dicyclohexyl-carbodiimide; In tetrahydrofuran; water;
DOI:10.1021/ja0118338

Reference yield:

: 107735-20-6
[(dimethylphenylsilyl)methyl]magnesium chloride

: 389807-13-0
(1'R,4R,2'E)-4-[1'-acetoxy-4'-(tert-butyldiphenylsilyloxy)but-2'-en-1'-yl]-4-(dimethylphenylsilyl)methyl-2-phenyl-4,5-dihydro-5-oxazolone

Guidance literature:: Multi-step reaction with 4 steps

1.1: 61 percent / tetrahydrofuran / 3 h / -78 - 0 °C

2.1: 94 percent / LiOH / tetrahydrofuran; H₂O / 8 h / 25 °C

3.1: 97 percent / DCC / tetrahydrofuran / 12 h / 25 °C

4.1: NaH / tetrahydrofuran / 25 °C / Irradiation

4.2: (η³-C3H5PdCl)2; (R,R)-1,2-(o-PPh2-C6H4-CO-NH)2-cyclohexane / tetrahydrofuran / 25 °C

4.3: 23 percent / tetrahydrofuran / 3 h / 0 °C

With lithium hydroxide; sodium hydride; dicyclohexyl-carbodiimide; In tetrahydrofuran; water;
DOI:10.1021/ja0118338